Exploring the TRAILs less travelled: TRAIL in cancer biology and therapy
S Von Karstedt, A Montinaro, H Walczak - Nature Reviews Cancer, 2017 - nature.com
The discovery that the tumour necrosis factor-related apoptosis-inducing ligand (TRAIL) can
induce apoptosis of cancer cells without causing toxicity in mice has led to the in-depth study …
induce apoptosis of cancer cells without causing toxicity in mice has led to the in-depth study …
The biochemistry of apoptosis
MO Hengartner - Nature, 2000 - nature.com
Apoptosis—the regulated destruction of a cell—is a complicated process. The decision to
die cannot be taken lightly, and the activity of many genes influence a cell's likelihood of …
die cannot be taken lightly, and the activity of many genes influence a cell's likelihood of …
Extrinsic versus intrinsic apoptosis pathways in anticancer chemotherapy
S Fulda, KM Debatin - Oncogene, 2006 - nature.com
Apoptosis or programmed cell death is a key regulator of physiological growth control and
regulation of tissue homeostasis. One of the most important advances in cancer research in …
regulation of tissue homeostasis. One of the most important advances in cancer research in …
Targeting apoptosis pathways in cancer therapy
IM Ghobrial, TE Witzig, AA Adjei - CA: a cancer journal for …, 2005 - Wiley Online Library
Apoptosis, or programmed cell death, is a mechanism by which cells undergo death to
control cell proliferation or in response to DNA damage. The understanding of apoptosis has …
control cell proliferation or in response to DNA damage. The understanding of apoptosis has …
Overview of cell death signaling pathways
Z Jin, WS El-Deiry - Cancer biology & therapy, 2005 - Taylor & Francis
Apoptosis plays an important role in development and maintenance of tissue homeostasis.
Intensive efforts have been made to explore the molecular mechanisms of the apoptotic …
Intensive efforts have been made to explore the molecular mechanisms of the apoptotic …
Targeting death and decoy receptors of the tumour-necrosis factor superfamily
A Ashkenazi - Nature Reviews Cancer, 2002 - nature.com
Cancer cells often develop resistance to chemotherapy or irradiation through mutations in
the p53 tumour-suppressor gene, which prevent apoptosis induction in response to cellular …
the p53 tumour-suppressor gene, which prevent apoptosis induction in response to cellular …
TRAIL and apoptosis induction by TNF-family death receptors
S Wang, WS El-Deiry - Oncogene, 2003 - nature.com
Tumor necrosis factor-related apoptosis-inducing ligand or Apo 2 ligand (TRAIL/Apo2L) is a
member of the tumor necrosis factor (TNF) family of ligands capable of initiating apoptosis …
member of the tumor necrosis factor (TNF) family of ligands capable of initiating apoptosis …
The TRAIL apoptotic pathway in cancer onset, progression and therapy
RW Johnstone, AJ Frew, MJ Smyth - Nature Reviews Cancer, 2008 - nature.com
Triggering of tumour cell apoptosis is the foundation of many cancer therapies. Death
receptors of the tumour necrosis factor (TNF) superfamily have been largely characterized …
receptors of the tumour necrosis factor (TNF) superfamily have been largely characterized …
Biological activities of green silver nanoparticles synthesized with Acorous calamus rhizome extract
JR Nakkala, R Mata, AK Gupta, SR Sadras - European journal of medicinal …, 2014 - Elsevier
Nanomedicine utilize biocompatible nanomaterials for diagnostic and therapeutic purposes.
This study reports the synthesis of silver nanoparticles using aqueous rhizome extract of …
This study reports the synthesis of silver nanoparticles using aqueous rhizome extract of …
Involvement of tumor necrosis factor-related apoptosis-inducing ligand in surveillance of tumor metastasis by liver natural killer cells
Tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) induces apoptosis in
various tumor cells in vitro, but its physiological role in tumor surveillance remains unknown …
various tumor cells in vitro, but its physiological role in tumor surveillance remains unknown …