Viscoelastic testing: Critical appraisal of new methodologies and current literature

GD Wool, T Carll - International Journal of Laboratory …, 2023 - Wiley Online Library
Abstract United States Food and Drug Administration (FDA)‐approved viscoelastic testing
(VET) methodologies have significantly changed in the last 10 years, with the availability of …

The yin and the yang of hemostasis in end-stage liver disease

FH Saner, E Scarlatescu, DC Broering… - Journal of clinical …, 2023 - mdpi.com
Patients with end-stage liver disease (ESLD) undergoing liver transplantation (LT) are prone
to thromboses both while on the waiting list and in the perioperative period. This …

R otational Thrombo E lastometry-guided blood component administration versus standard of care in patients with C irrhosis and coagulopathy undergoing I nvasive P …

N Janko, A Majeed, W Kemp, C Hogan, H Nandurkar… - Trials, 2023 - Springer
Background Patients with cirrhosis often undergo invasive procedures both for management
of complications of their advanced liver disease, including treatment for hepatocellular …

[HTML][HTML] Approach to thromboelastography-based transfusion in cirrhosis: An alternative perspective on coagulation disorders

S Kataria, D Juneja, O Singh - World Journal of Gastroenterology, 2023 - ncbi.nlm.nih.gov
Viscoelastic tests, specifically thromboelastography and rotational thromboelastometry, are
increasingly being used in the management of postoperative bleeding in surgical intensive …

Does the use of viscoelastic haemostatic assays for risk periprocedural haemostasis management in liver disease improve clinical outcomes?

S Maynard, E Marrinan, L Roberts… - Transfusion Medicine …, 2024 - Elsevier
Routine haemostasis parameters such as prothrombin time and fibrinogen are frequently
abnormal in patients with chronic liver disease and have been demonstrated to be poor …

Diagnosis and management of pediatric acute liver failure: consensus recommendations of the Indian Society of Pediatric Gastroenterology, Hepatology, and Nutrition …

BB Lal, R Khanna, V Sood, S Alam, A Nagral… - Hepatology …, 2024 - Springer
Timely diagnosis and management of pediatric acute liver failure (PALF) is of paramount
importance to improve survival. The Indian Society of Pediatric Gastroenterology …

Rotational thromboelastometry predicts future bleeding events in patients with cirrhosis

N Janko, A Majeed, I Commins, P Gow… - Scandinavian Journal …, 2024 - Taylor & Francis
Background and aims Patients with cirrhosis of the liver are in a delicate state of rebalanced
haemostasis and are at risk of developing both bleeding and thrombotic complications …

[HTML][HTML] Serial rotational thromboelastometry measurements show worsening hypocoagulability in acute-on-chronic liver failure and are associated with the severity of …

G Kampelos, L Vasilieva, T Alexopoulos… - Annals of …, 2024 - ncbi.nlm.nih.gov
Background Viscoelastic tests are used to better understand the complex picture of
hemostasis in cirrhosis. Limited data exist regarding the clinical relevance of rotational …

Thromboelastography-Guided versus Standard-of-Care or On-Demand Platelet Transfusion in Patients with Cirrhosis and Thrombocytopenia Undergoing Procedures …

S Biswas, A Anand, M Vaishnav, S Mehta… - Journal of Vascular and …, 2024 - Elsevier
Purpose To determine the rate of platelet transfusion in patients with cirrhosis and severe
thrombocytopenia (platelet counts< 50× 10 9/L) undergoing high-risk invasive procedures …

A combination of clot formation abnormalities in thromboelastometry has a high prognostic value in patients with acute-on-chronic liver failure

G Kampelos, T Alexopoulos, L Vasilieva… - European Journal of …, 2024 - journals.lww.com
Background Global coagulation tests offer a better tool to assess procoagulant and
anticoagulant pathways, fibrinolysis and clot firmness and evaluate more accurately …