Molecular diagnosis of visceral leishmaniasis

S Sundar, OP Singh - Molecular diagnosis & therapy, 2018 - Springer
Visceral leishmaniasis (VL), a deadly parasitic disease, is a major public health concern
globally. Countries affected by VL have signed the London Declaration on Neglected …

Recent advances and new strategies in Leishmaniasis diagnosis

RCF De Brito, RDO Aguiar-Soares… - Applied Microbiology …, 2020 - Springer
Leishmaniasis is a set of complex and multifaceted syndromes, with different clinical
manifestations, caused by different species of the genus Leishmania spp. that can be …

Leishmaniasis in the United States: emerging issues in a region of low endemicity

JM Curtin, NE Aronson - Microorganisms, 2021 - mdpi.com
Leishmaniasis, a chronic and persistent intracellular protozoal infection caused by many
different species within the genus Leishmania, is an unfamiliar disease to most North …

Combining epidemiology with basic biology of sand flies, parasites, and hosts to inform leishmaniasis transmission dynamics and control

O Courtenay, NC Peters, ME Rogers, C Bern - PLoS pathogens, 2017 - journals.plos.org
Quantitation of the nonlinear heterogeneities in Leishmania parasites, sand fly vectors, and
mammalian host relationships provides insights to better understand leishmanial …

Real-time PCR in detection and quantitation of Leishmania donovani for the diagnosis of Visceral Leishmaniasis patients and the monitoring of their response to …

F Hossain, P Ghosh, MAA Khan, MS Duthie, AC Vallur… - PloS one, 2017 - journals.plos.org
Sustained elimination of Visceral Leishmaniasis (VL) requires the reduction and control of
parasite reservoirs to minimize the transmission of Leishmania donovani infection. A simple …

Blood parasite load as an early marker to predict treatment response in visceral leishmaniasis in Eastern Africa

L Verrest, AE Kip, AM Musa, GJ Schoone… - Clinical Infectious …, 2021 - academic.oup.com
Background To expedite the development of new oral treatment regimens for visceral
leishmaniasis (VL), there is a need for early markers to evaluate treatment response and …

The activity of encapsulated meglumine antimoniate in stearylamine-bearing liposomes against cutaneous leishmaniasis in BALB/c mice

SA Moosavian, M Fallah, MR Jaafari - Experimental parasitology, 2019 - Elsevier
Topical treatment of cutaneous leishmaniasis has demonstrated appropriate alternative for
reducing toxicity of conventional treatments, improving patients' compliance and reducing …

Causes and consequences of higher Leishmania infantum burden in patients with kala‐azar: a study of 625 patients

DA Zacarias, N Rolão, FA de Pinho… - Tropical Medicine & …, 2017 - Wiley Online Library
Background An infected host's Leishmania infantum load in blood is considered to be an
estimate of his or her total parasite burden. Therefore, the measurement of blood parasite …

Molecular Tracking of the Leishmania Parasite

S Moulik, S Sengupta, M Chatterjee - Frontiers in Cellular and …, 2021 - frontiersin.org
With the Visceral Leishmaniasis/Kala-azar Elimination Program in South Asia in its
consolidation phase, the focus is mainly on case detection, vector control, and identifying …

Development of real-time PCR assays for evaluation of immune response and parasite load in golden hamster (Mesocricetus auratus) infected by Leishmania …

RP Ribeiro-Romão, AF Saavedra, AM Da-Cruz… - Parasites & vectors, 2016 - Springer
Background Cutaneous leishmaniasis (CL) is a neglected disease with a broad spectrum of
clinical manifestations, ranging from small cutaneous nodules to severe mucosal tissue …