Osteoarthritis (OA) is a chronic, prevalent, debilitating joint disease characterized by
progressive cartilage degradation, subchondral bone remodeling, bone marrow lesions …

Garlic is widely accepted as a functional food and an excellent source of pharmacologically
active ingredients. Diallyl disulfide (DADS), a major bioactive component of garlic, has …

Abstract Hit, Lead & Candidate Discovery This study investigated the effects of a natural
phenolic compound quercetin on surgical‐induced osteoarthritis (OA) in rabbits. Forty‐eight …

Background: Articular cartilage lesions occur frequently but unfortunately damaged cartilage
has a very limited intrinsic repair capacity. Therefore, there is a high need to develop …

Cisplatin resistance is a daunting obstacle in cancer therapy and one of the major causes for
treatment failure due to the inadequate drug activity and apoptosis induction. To overcome …

Pulmonary fibrosis (PF) is the end stage of severe lung diseases, in which the lung
parenchyma is replaced by fibrous scar tissue. The result is a remarkable reduction in …

Diallyl disulfide (DADS), an oil-soluble sulfur compound that is responsible for the biological
effects of garlic, displays numerous biological activities, among which its anti-cancer …

Skeletal homeostasis is closely effectuated by the regulation of bone formation and bone
resorption. Osteoclasts are multinuclear giant cells responsible for bone resorption …

Objective To investigate the correlation between melatonin and osteoarthritis (OA) in rats. To
explore the relevant mechanisms in the occurrence and development of osteoarthritis in rats …

Cartilage defects in temporomandibular disorders (TMD) lead to chronic pain and seldom
heal. Synovium‐derived mesenchymal stem cells (SMSCs) exhibit superior chondrogenesis …