In pathogenic simian immunodeficiency virus (SIV) and human immunodeficiency virus
(HIV) infections, the translocation of microbial products from the gastrointestinal (GI) tract to …

For more than two decades, CD4 cell count measurements have been central to
understanding HIV disease progression, making important clinical decisions, and monitoring …

Background The efficacy and toxic effects of nucleoside reverse-transcriptase inhibitors
(NRTIs) are uncertain when these agents are used with a protease inhibitor in second-line …

Background Predictors of immuno-virologic outcomes and discordance and their
associations with clinical, demographic, socio-economic and behavioral risk factors are not …

Most patients with human immunodeficiency virus (HIV) who remain CD4+ T-cell deficient
on antiretroviral therapy (ART) exhibit marked immune activation. As CD4+ T-cell activation …

The aim was to analyze clinical complications in HIV-infected subjects who persistently
maintain low CD4 levels despite virological response to cART in the Spanish CoRIS cohort …

Background A discordant immune response (DIR) is a failure to satisfactorily increase CD4
counts on ART despite successful virological control. Literature on the clinical effects of DIR …

Introduction Co-trimoxazole prophylaxis is used to reduce morbidity and mortality in people
with HIV. We systematically reviewed three topics related to co-trimoxazole prophylaxis to …

Clinical outcomes are inferior for individuals with HIV having suboptimal CD4 T-cell recovery
during antiretroviral therapy (ART). We investigated if the levels of infection and the …

Background: Terms and criteria to classify people living with HIV on antiretroviral therapy
who fail to achieve satisfactory CD4+ T-cell counts are heterogeneous, and need revision …