Comprehensive review on the anti-bacterial activity of 1, 2, 3-triazole hybrids
B Zhang - European Journal of Medicinal Chemistry, 2019 - Elsevier
Bacterial infections, caused predominately by Gram-positive and Gram-negative organisms,
are proliferation of harmful strains of bacteria on or inside the body. Hospital-acquired and …
are proliferation of harmful strains of bacteria on or inside the body. Hospital-acquired and …
Antibacterial activity study of 1, 2, 4-triazole derivatives
F Gao, T Wang, J Xiao, G Huang - European journal of medicinal chemistry, 2019 - Elsevier
Antibiotics are commonly used to fight against bacterial infections, but bacteria have already
been resistant to almost all antibiotics due to abuse of antibiotics. 1, 2, 4-Triazole derived …
been resistant to almost all antibiotics due to abuse of antibiotics. 1, 2, 4-Triazole derived …
Design, synthesis, molecular modeling, anticancer studies, and density functional theory calculations of 4-(1, 2, 4-triazol-3-ylsulfanylmethyl)-1, 2, 3-triazole derivatives
A Al Sheikh Ali, D Khan, A Naqvi, FF Al-Blewi… - ACS …, 2020 - ACS Publications
New conjugates of substituted 1, 2, 3-triazoles linked to 1, 2, 4-triazoles were synthesized
starting from the appropriate S-propargylated 1, 2, 4-triazoles 7 and 8. Ligation of 1, 2, 4 …
starting from the appropriate S-propargylated 1, 2, 4-triazoles 7 and 8. Ligation of 1, 2, 4 …
Recent progress in 1H-1, 2, 3-triazoles as potential antifungal agents
The need to overcome ever-increasing cases of antifungal resistance and circumvent side
effects and drug interactions related to currently available drugs has impelled the demand to …
effects and drug interactions related to currently available drugs has impelled the demand to …
Design, synthesis, DNA binding, modeling, anticancer studies and DFT calculations of Schiff bases tethering benzothiazole-1, 2, 3-triazole conjugates
MA Almehmadi, A Aljuhani, SY Alraqa, I Ali… - Journal of Molecular …, 2021 - Elsevier
In an attempt to design and prepare a new library of anticancer candidates, focused
thiopropargylated benzothiazole was reacted with ethyl azidoacetate and/or ethyl …
thiopropargylated benzothiazole was reacted with ethyl azidoacetate and/or ethyl …
Novel scaffold hopping of potent benzothiazole and isatin analogues linked to 1, 2, 3-triazole fragment that mimic quinazoline epidermal growth factor receptor …
N Rezki, MA Almehmadi, S Ihmaid, AM Shehata… - Bioorganic …, 2020 - Elsevier
A series of benzothiazole/isatin linked to 1, 2, 3-triazole moiety and terminal sulpha drugs 5a-
e and 6a-e were synthesized and evaluated for cytotoxic activity against a panel of cancer …
e and 6a-e were synthesized and evaluated for cytotoxic activity against a panel of cancer …
A review on the efficacy and medicinal applications of metal-based triazole derivatives
Recently, there has been increased microbial and multidrug resistance in clinical field that
negatively affects health because it leads to a variety of diseases due to inefficient mode of …
negatively affects health because it leads to a variety of diseases due to inefficient mode of …
Chemistry and biological activities of 1, 2, 4-triazolethiones—antiviral and anti-infective drugs
Mercapto-substituted 1, 2, 4-triazoles are very interesting compounds as they play an
important role in chemopreventive and chemotherapeutic effects on cancer. In recent …
important role in chemopreventive and chemotherapeutic effects on cancer. In recent …
Design of molecular hybrids of phthalimide-triazole agents with potent selective MCF-7/HepG2 cytotoxicity: Synthesis, EGFR inhibitory effect, and metabolic stability
SK Ihmaid, SY Alraqa, MR Aouad, A Aljuhani… - Bioorganic …, 2021 - Elsevier
This study reports an efficient and convenient click chemistry synthesis of a novel series of
phthalimide scaffold linked to 1, 2, 3 triazole ring and terminal lipophilic fragments …
phthalimide scaffold linked to 1, 2, 3 triazole ring and terminal lipophilic fragments …
Design, synthesis, ADME prediction and pharmacological evaluation of novel benzimidazole-1, 2, 3-triazole-sulfonamide hybrids as antimicrobial and antiproliferative …
FF Al-Blewi, MA Almehmadi, MR Aouad… - Chemistry Central …, 2018 - Springer
Background Nitrogen heterocyclic rings and sulfonamides have attracted attention of several
researchers. Results A series of regioselective imidazole-based mono-and bis-1, 4 …
researchers. Results A series of regioselective imidazole-based mono-and bis-1, 4 …