Insulin resistance and the polycystic ovary syndrome revisited: an update on mechanisms and implications
E Diamanti-Kandarakis, A Dunaif - Endocrine reviews, 2012 - academic.oup.com
Polycystic ovary syndrome (PCOS) is now recognized as an important metabolic as well as
reproductive disorder conferring substantially increased risk for type 2 diabetes. Affected …
reproductive disorder conferring substantially increased risk for type 2 diabetes. Affected …
[HTML][HTML] The complex roles of adipokines in polycystic ovary syndrome and endometriosis
S Schüler-Toprak, O Ortmann, C Buechler, O Treeck - Biomedicines, 2022 - mdpi.com
Polycystic ovary syndrome (PCOS) and endometriosis are frequent diseases of the female
reproductive tract causing high morbidity as they can significantly affect fertility and quality of …
reproductive tract causing high morbidity as they can significantly affect fertility and quality of …
BMP4 and BMP antagonists regulate human white and beige adipogenesis
B Gustafson, A Hammarstedt, S Hedjazifar… - Diabetes, 2015 - Am Diabetes Assoc
The limited expandability of subcutaneous adipose tissue, due to reduced ability to recruit
and differentiate new adipocytes, prevents its buffering effect in obesity and is characterized …
and differentiate new adipocytes, prevents its buffering effect in obesity and is characterized …
Exercise induces a marked increase in plasma follistatin: evidence that follistatin is a contraction-induced hepatokine
J Hansen, C Brandt, AR Nielsen, P Hojman… - …, 2011 - academic.oup.com
Follistatin is a member of the TGF-β super family and inhibits the action of myostatin to
regulate skeletal muscle growth. The regulation of follistatin during physical exercise is …
regulate skeletal muscle growth. The regulation of follistatin during physical exercise is …
Emerging roles for the transforming growth factor-β superfamily in regulating adiposity and energy expenditure
N Zamani, CW Brown - Endocrine reviews, 2011 - academic.oup.com
Members of the TGF-β superfamily regulate many aspects of development, including
adipogenesis. Studies in cells and animal models have characterized the effects of …
adipogenesis. Studies in cells and animal models have characterized the effects of …
Bone morphogenetic protein and growth differentiation factor cytokine families and their protein antagonists
CC Rider, B Mulloy - Biochemical Journal, 2010 - portlandpress.com
The BMPs (bone morphogenetic proteins) and the GDFs (growth and differentiation factors)
together form a single family of cystine-knot cytokines, sharing the characteristic fold of the …
together form a single family of cystine-knot cytokines, sharing the characteristic fold of the …
Circulating follistatin is liver-derived and regulated by the glucagon-to-insulin ratio
JS Hansen, S Rutti, C Arous… - The Journal of …, 2016 - academic.oup.com
Context: Follistatin is a plasma protein recently reported to increase under conditions with
negative energy balance, such as exercise and fasting in humans. Currently, the perception …
negative energy balance, such as exercise and fasting in humans. Currently, the perception …
Characterization of the Wnt inhibitors secreted frizzled-related proteins (SFRPs) in human adipose tissue
A Ehrlund, N Mejhert, S Lorente-Cebrian… - The Journal of …, 2013 - academic.oup.com
Context: Wnt signaling regulates adipogenesis and adipocyte function. Secreted frizzled-
related proteins (SFRPs) are a family of secreted proteins (SFRP1-5) that bind and inhibit …
related proteins (SFRPs) are a family of secreted proteins (SFRP1-5) that bind and inhibit …
Beyond the bone: Bone morphogenetic protein signaling in adipose tissue
AM Blázquez‐Medela, M Jumabay… - Obesity …, 2019 - Wiley Online Library
The bone morphogenetic proteins (BMPs) belong to the same superfamily as related to
transforming growth factor β (TGFβ), growth and differentiation factors (GDFs), and activins …
transforming growth factor β (TGFβ), growth and differentiation factors (GDFs), and activins …
Activin a plays a critical role in proliferation and differentiation of human adipose progenitors
LE Zaragosi, B Wdziekonski, P Villageois… - Diabetes, 2010 - Am Diabetes Assoc
OBJECTIVE Growth of white adipose tissue takes place in normal development and in
obesity. A pool of adipose progenitors is responsible for the formation of new adipocytes and …
obesity. A pool of adipose progenitors is responsible for the formation of new adipocytes and …