The current understanding of lactate extends from its origins as a byproduct of glycolysis to
its role in tumor metabolism, as identified by studies on the Warburg effect. The lactate …

Metabolites of glycolytic metabolism have been identified as signaling molecules and
regulators of gene expression, in addition to their basic function as major energy and …

Mesenchymal stem cells (MSCs) can be derived from various adult tissues with multipotent
and self‐renewal abilities. The characteristics of presenting no major ethical concerns …

Mesenchymal stem cells (MSCs; also referred to as mesenchymal stromal cells) have
attracted much attention for their ability to regulate inflammatory processes. Their therapeutic …

Normal wound healing is a dynamic and complex multiple phase process involving
coordinated interactions between growth factors, cytokines, chemokines, and various cells …

Mesenchymal stem cells (MSCs) are multipotent stem cells characterized by self‐renewal,
production of clonal cell populations, and multilineage differentiation. They exist in nearly all …

Recent evidence indicates that mitochondria lie at the heart of immunity. Mitochondrial DNA
acts as a danger-associated molecular pattern (DAMP), and the mitochondrial outer …

Lack of immune system cells or impairment in differentiation of immune cells is the basis for
many chronic diseases. Metabolic changes could be the root cause for this immune cell …

Many tumors evolve sophisticated strategies to evade the immune system, and these
represent major obstacles for efficient antitumor immune responses. Here we explored a …

The link between cancer metabolism and immunosuppression, inflammation and immune
escape has generated major interest in investigating the effects of low pH on tumor …