The growing prevalence of hypertension, heart disease, diabetes, and obesity along with an
aging population is leading to a higher incidence of renal diseases in society. Chronic …

Patients with chronic kidney disease (CKD) are at an increased cardiovascular risk
compared with the general population, which is driven, at least in part, by mechanisms that …

Background Epigenetics regulating gene expression plays important role in kidney fibrosis.
Natural products originating from diverse sources including plants and microorganisms are …

Liver fibrosis, characterized by scar tissue formation, can ultimately result in liver failure. It's a
major cause of morbidity and mortality globally, often associated with chronic liver diseases …

Fibrosis is a pathological condition that is characterized by an abnormal buildup of
extracellular matrix (ECM) components, such as collagen, in tissues. This condition affects …

We have recently demonstrated that Jumonji domain‐containing protein D3 (JMJD3), a
histone demethylase of histone H3 on lysine 27 (H3K27me3), is protective against renal …

Liver fibrosis is caused by chronic liver damage and results in the aberrant accumulation of
extracellular matrix during disease progression. Despite the identification of the HAT …

Kidney fibrosis is a complex polyetiological progressive disease manifesting as an
intraorgan proliferation of the connective tissue with the appearance of cicatricial changes …