Gap junctions are plasma membrane spatial microdomains constructed of assemblies of
channel proteins called connexins in vertebrates and innexins in invertebrates. The …

Intercellular calcium (Ca2+) waves (ICWs) represent the propagation of increases in
intracellular Ca2+ through a syncytium of cells and appear to be a fundamental mechanism …

A crucial early wound response is the recruitment of inflammatory cells drawn by danger
cues released by the damaged tissue. Hydrogen peroxide (H 2 O 2) has recently been …

Connexin channels are known to be permeable to a variety of cytoplasmic molecules. The
first observation of second messenger junctional permeability, made∼ 30 years ago …

Gap junctions are clusters of aqueous channels that connect the cytoplasm of adjoining
cells. Each cell contributes a hemichannel, or connexon, to each cell–cell channel. The cell …

This paper presents unique approaches to enable control and quantification of ultrasound-
mediated cell membrane disruption, or sonoporation, at the single-cell level. Ultrasound …

Endoplasmic reticulum stress (ERS) has a pathophysiological role in obesity-associated
insulin resistance. Yet, the coordinated tissue response to ERS remains unclear. Increased …

Macroautophagy (hereafter referred to as autophagy) is an evolutionarily conserved
intracellular bulk degradation pathway that plays critical roles in eliminating intracellular …

Intercellular Ca2+ waves in astrocytes are thought to serve as a pathway of long-range
signaling. The waves can propagate by the diffusion of molecules through gap junctions and …

Aims Intercellular interactions between cardiomyocytes (CMs) and cardiofibroblasts (FBs)
are important in the physiological and pathophysiological heart. Understanding such …