Development of a customizable mouse backbone spectral flow cytometry panel to delineate immune cell populations in normal and tumor tissues

ALF Longhini, I Fernández-Maestre… - Frontiers in …, 2024 - frontiersin.org
Introduction In vivo studies of cancer biology and assessment of therapeutic efficacy are
critical to advancing cancer research and ultimately improving patient outcomes. Murine …

Inhibition of Enhancer of Zeste Homolog 2 Induces Blast Differentiation, Impairs Engraftment and Prolongs Survival in Murine Models of Acute Myeloid Leukemia

S Fobare, OA Elgamal, M Wunderlich, E Stahl… - Cancers, 2024 - mdpi.com
Simple Summary Acute myeloid leukemia (AML) is the abnormal growth of immature blood
cells characterized by a block in differentiation. The therapy options to treat AML have …

Case report: single-cell RNA sequencing of PBMCs highlights monocyte gene expression alterations in a type A HBV-ACLF patient

Y Wang, Z Hao, J Liu, X Kang, C Ji, Y Guo, Z Chen… - Heliyon, 2024 - cell.com
Hepatitis B Virus-related acute-on-chronic liver failure (HBV-ACLF) is a severe complication
with high fatality rates. However, the underlying mechanisms are still elusive and require …

[HTML][HTML] Differentiation Therapy in Acute Myeloid Leukemia: Not Just for APL Anymore

PJ Sung - Differentiation, 2024 - quinquelles.cl
A hallmark of acute myeloid leukemia (AML) is a maturation arrest of myeloid-committed
hematopoietic cells, and the specific sensitivity of acute promyelocytic leukemia (APL) to …