Vesicular approach of cubosomes, its components, preparation techniques, evaluation and their appraisal for targeting cancer cells

S Iqbal, M Zaman, MA Waqar, HS Sarwar… - Journal of Liposome …, 2024 - Taylor & Francis
Cancer has been characterized by abnormal and uncontrolled proliferation of cells. Majority
of drugs given through chemotherapy produce unwanted and adverse effects of …

Folate decorated lipid chitosan hybrid nanoparticles of 5-fluorouracil for enhanced anticancer efficacy against colon cancer

S Khan, A Madni, H Shah, N Jan, A Shafiq… - International Journal of …, 2022 - Elsevier
The study aimed to develop folate decorated lipid chitosan hybrid nanoparticles for targeted
delivery of 5-fluorouracil in colon cancer by utilizing the overexpressed folate receptors on …

Lipid poly (ɛ-caprolactone) hybrid nanoparticles of 5-fluorouracil for sustained release and enhanced anticancer efficacy

S Khan, MN Aamir, A Madni, N Jan, A Khan, A Jabar… - Life Sciences, 2021 - Elsevier
Aims The present study aimed to develop and characterize poly (ɛ-caprolactone)(PCL)
based lipid polymer hybrid nanoparticles for sustained delivery and in-vitro anti-cancer …

Solid lipid-based nanoparticulate system for sustained release and enhanced in-vitro cytotoxic effect of 5-fluorouracil on skin Melanoma and squamous cell …

A Ali, A Madni, H Shah, T Jamshaid, N Jan, S Khan… - Plos one, 2023 - journals.plos.org
The present study aimed to prepare solid lipid-based nanoparticles (SLNs) using Precirol®
ATO 5 as solid lipid and Poloxamer 188 and Tween 80 as surfactant and co-surfactant …

[HTML][HTML] Anticancer drug delivery: Investigating the impacts of viscosity on lipid-based formulations for pulmonary targeting

AM Thevarkattil, S Yousaf, C Houacine, W Khan… - International Journal of …, 2024 - Elsevier
Pulmonary drug delivery via aerosolization is a non-intrusive method for achieving localized
and systemic effects. The aim of this study was to establish the impact of viscosity as a novel …

Core-shell Pluronic F127/chitosan based nanoparticles for effective delivery of methotrexate in the management of rheumatoid arthritis

A Shafiq, A Madni, S Khan, H Sultana, H Shah… - International Journal of …, 2022 - Elsevier
This study was designed to improve oral bioavailability of the methotrexate (MTX) by
sustaining its release profile and integration into core-shell polymeric nanoparticles. The self …

Thermo-responsive sol-gel-based nano-carriers containing terbinafine HCl: formulation, in vitro and ex vivo characterization, and antifungal activity

M Bajwa, N Tabassam, H Hameed, A Irfan, M Zaman… - Gels, 2023 - mdpi.com
The current research aims to create a sol-gel-based nanocarrier containing terbinafine
formulated for transdermal delivery of the drug into the skin. Sol-gel-based nanocarriers …

Proliposome-Based Nanostrategies: Challenges and Development as Drug Delivery Systems

M Choudhary, N Chaurawal, MA Barkat, K Raza - AAPS PharmSciTech, 2022 - Springer
Many attempts have been made to the refinement of liposomal stability. In 1986, Payne et al.
developed the approach of proliposomes to derelict the physicochemical instability …

Synergistic strategies for enhanced liver cancer therapy with sorafenib/resveratrol PEGylated liposomes in vitro and in vivo

AA Alrashidi, SZ Alavi, M Koohi, A Raza… - Journal of Drug Delivery …, 2024 - Elsevier
This study investigates the therapeutic efficacy of sorafenib (Sr) and resveratrol (Rv)
encapsulated in liposomal formulations for liver cancer treatment. In vitro release profiles …

[Retracted] Synthesis and Evaluation of Finasteride‐Loaded HPMC‐Based Nanogels for Transdermal Delivery: A Versatile Nanoscopic Platform

A Ahmad, M Ahmad, MU Minhas… - BioMed Research …, 2022 - Wiley Online Library
Herein, we report nanogels comprising diverse feed ratio of polymer hydroxypropyl
methylcellulose (HPMC), monomer acrylic acid (AA), and cross‐linker methylene …