The steroid superfamily includes a wide range of compounds that are essential for living
organisms of the animal and plant kingdoms. Structural modifications of steroids highly affect …

Steroids are perhydro-1, 2-cyclopentanophenanthrene derivatives that are almost
exclusively synthesised by eukaryotic organisms. Since the start of the Anthropocene, the …

Enzymatic hydroxylation of activated and nonactivated sp3-carbons attracts keen interest
from the chemistry community as it is one of the most challenging tasks in organic synthesis …

The challenge of activating inert C–H bonds motivates a study of catalysts that draws from
what can be accomplished by natural enzymes and translates these advantageous features …

Molybdenum-and tungsten-dependent proteins catalyze essential processes in living
organisms and biogeochemical cycles. Among these enzymes, members of the dimethyl …

Pterin based molybdenum cofactor found in the molybdenum dependent enzymes catalyzes
the oxo-transferase and hydroxylase activity. For tungsten, the pterin based tungsten …

hydroxyvitamin D 3 has attracted considerable attention due to its great medical value and
huge market demand in animal husbandry. Microbial production of 25-hydroxyvitamin D 3 …

Δ1-Dehydrogenation of 3-ketosteroids catalyzed by flavin adenine dinucleotide (FAD)-
dependent 3-ketosteroid dehydrogenases (Δ1-KSTD) is a crucial step in steroid degradation …

3-Ketosteroid Δ1-dehydrogenases (KstD) are important microbial flavin enzymes that initiate
the metabolism of steroid ring A and find application in the synthesis of steroid drugs. We …

Anaerobic toluene degradation is initiated by adding toluene to fumarate via the glycyl
radical enzyme benzylsuccinate synthase (BSS). We developed a recombinant production …