Copper is found in all living organisms and is a crucial trace element in redox chemistry,
growth and development. It is important for the function of several enzymes and proteins …

Metal-based antitumor drugs play a relevant role in antiblastic chemotherapy. Cisplatin is
regarded as one of the most effective drugs, even if severe toxicities and drug resistance …

The synthesis of two groups of structure hybrids comprising basically the antipyrine moiety
attached to either polysubstituted thiazole or 2, 5-disubstituted-1, 3, 4-thiadiazole …

Thiabendazole (TBZH) reacts with iron (III) nitrate causing protonation of the ligand to yield
the nitrate salt [TBZH2NO3](1). Reaction of TBZH with copper (II) acetate results in the …

New thiazoline derivatives 7a-c, and thiophenes 9a-c linked to indole moiety were easily
prepared via the reaction of the acrylamide derivative 3 with phenacyl bromides 4a-c …

Abstract Thiazolo [4, 5-d] pyrimidines are fused heterocyclic ring-systems that can be viewed
at the first glance as purine isosteres. They are the 7 thia-analogs of purines via the …

Copper is a necessary micronutrient for maintaining the well-being of the human body. The
biological activity of organic ligands, especially their anticancer activity, is often enhanced …

Two copper (II) complexes with tetradentate 1, 4-disubstituted-1, 2, 3-triazole ligands,[Cu L
(MeCN)](ClO4) 2 (1) and [Cu L′](ClO4) 2 (2), have been prepared and characterized by …

1H-Benzimidazol-2-ylmethyl diethyl phosphate (2-BimOpe) was synthesized via
condensation of phosphorochloridic acid diethyl ester with 2-benzimidazolemethanol in the …

Nicotinic acid esters 3a–c were prepared by the reaction of pyridine-2 (1 H)-thione derivative
1 with α-halo-reagents 2a–c. Compounds 3a–c underwent cyclization to the corresponding …