Effect of diphtheria toxin T-domain on endosomal pH
A key step in the mode of cytotoxic action of diphtheria toxin (Dt) is the transfer of its catalytic
domain (cd) from endosomes into the cytosol. the main activity in this process is performed …
domain (cd) from endosomes into the cytosol. the main activity in this process is performed …
[PDF][PDF] Epitopes identification of broadly neutralizing monoclonal antibodies against Corynebacterium diphtheriae exotoxin
YS Kulyk, AA Siromolot, DV Kolybo - Biotechnologia Acta, 2022 - jnas.nbuv.gov.ua
Aim. In this study we focused on the search of binding sites identification of anti diphtheria
toxin monoclonal antibodies and their neutralizing activity to block binding of recombinant …
toxin monoclonal antibodies and their neutralizing activity to block binding of recombinant …
EPIDEMIOLOGY OF DIPHTHERIA IN GENRAL POPULATION OF BANNU DIVISION AND IDPs OF NORTH WAZIRISTAN AGENCY (NWA), PAKISTAN
R Ali, A ZIA-UR-RAHMAN - FUUAST Journal of Biology, 2018 - fuuastjb.org
The aim of the current study was to investigate mortality rate and to understand the causes of
persistence of diphtheria in Bannu division and to enlighten some strategies to prevent …
persistence of diphtheria in Bannu division and to enlighten some strategies to prevent …
Biological properties and medical application of diphtheria toxin derivatives
KY Manoilov - Biotechnologia Acta, 2018 - cyberleninka.ru
The aim of the review was to analyze the literature data related to the application of a variety
of diphtheria toxin derivatives. Although the studies interaction with sensitive and resistant …
of diphtheria toxin derivatives. Although the studies interaction with sensitive and resistant …
Necessity of translocation domain for realisation of cytostatic effect of non-toxic derivatives of diphtheria toxin
The aim of the work was to evaluate in vitro the cytostatic effect of recombinant fragments of
the non-toxic point mutant of diphtheria toxin CRM197, which was suggested as a potent …
the non-toxic point mutant of diphtheria toxin CRM197, which was suggested as a potent …
Enhancement of internalization of diphtheria toxin recombinant fragments in sensitive cells mediated by toxin's T-domain
KY Manoilov, AJ Labyntsev… - The Ukrainian …, 2017 - irbis-nbuv.gov.ua
Subunit B of diphtheria toxin (DT) and its R-domain differ by the presence of T-domain. The
aim of the present work was to analyze the interaction of these toxin fragments with …
aim of the present work was to analyze the interaction of these toxin fragments with …