The neurotransmitter dopamine is a key factor in central nervous system (CNS) function,
regulating many processes including reward, movement, and cognition. Dopamine also …

Melanin pigment plays a critical role in the protection against the harmful effects of ultraviolet
radiation and other environmental stressors. It is produced by the enzymatic transformation …

During oncogenesis, cancer not only escapes the body's regulatory mechanisms, but also
gains the ability to affect local and systemic homeostasis. Specifically, tumors produce …

The skin is the largest organ and has a key protective role. Similar to any other tissue, the
skin is influenced not only by intrinsic/chronological aging, but also by extrinsic aging …

Endogenous photosensitizers play a critical role in both beneficial and harmful light-induced
transformations in biological systems. Understanding their mode of action is essential for …

The skin, which is comprised of the epidermis, dermis, and subcutaneous tissue, is the
largest organ in the human body and it plays a crucial role in the regulation of the body's …

The skin, being the largest organ in the human body, is exposed to the environment and
suffers from both intrinsic and extrinsic aging factors. The skin aging process is …

Melanogenesis is a process to synthesize melanin, which is a primary responsible for the
pigmentation of human skin, eye and hair. Although numerous enzymatic catalyzed and …

Melanocytes are melanin-producing cells found in skin, hair follicles, eyes, inner ear, bones,
heart and brain of humans. They arise from pluripotent neural crest cells and differentiate in …

The skin, a self-regulating protective barrier organ, is empowered with sensory and
computing capabilities to counteract the environmental stressors to maintain and restore …