Immune regulation of skin wound healing: mechanisms and novel therapeutic targets
J Larouche, S Sheoran, K Maruyama… - Advances in wound …, 2018 - liebertpub.com
Significance: The immune system plays a central role in orchestrating the tissue healing
process. Hence, controlling the immune system to promote tissue repair and regeneration is …
process. Hence, controlling the immune system to promote tissue repair and regeneration is …
[HTML][HTML] Progesterone-related immune modulation of pregnancy and labor
NM Shah, PF Lai, N Imami, MR Johnson - Frontiers in endocrinology, 2019 - frontiersin.org
Pregnancy involves a complex interplay between maternal neuroendocrine and
immunological systems in order to establish and sustain a growing fetus. It is thought that the …
immunological systems in order to establish and sustain a growing fetus. It is thought that the …
[HTML][HTML] Accelerated burn wound healing with photobiomodulation therapy involves activation of endogenous latent TGF-β1
The severity of tissue injury in burn wounds from associated inflammatory and immune
sequelae presents a significant clinical management challenge. Among various biophysical …
sequelae presents a significant clinical management challenge. Among various biophysical …
TGF Beta− 1,− 2 and− 3 in the Modulation of Fibrosis in the Cornea and Other Organs
SE Wilson - Experimental eye research, 2021 - Elsevier
Abstract The TGF beta-1,-2 and-3 isoforms are transcribed from different genes but bind to
the same receptors and signal through the same canonical and non-canonical signal …
the same receptors and signal through the same canonical and non-canonical signal …
Regulation of innate and adaptive immunity by TGFβ
A Kelly, SA Houston, E Sherwood, J Casulli… - Advances in …, 2017 - Elsevier
Immune regulation by cytokines is crucial in maintaining immune homeostasis, promoting
responses to infection, resolving inflammation, and promoting immunological memory …
responses to infection, resolving inflammation, and promoting immunological memory …
[HTML][HTML] TGFβ signaling pathways in human health and disease
PY Chen, L Qin, M Simons - Frontiers in molecular biosciences, 2023 - frontiersin.org
Transforming growth factor beta (TGFβ) is named for the function it was originally discovered
to perform-transformation of normal cells into aggressively growing malignant cells. It …
to perform-transformation of normal cells into aggressively growing malignant cells. It …
[HTML][HTML] Transforming growth factor-β3 regulates adipocyte number in subcutaneous white adipose tissue
White adipose tissue (WAT) mass is determined by adipocyte size and number. While
adipocytes are continuously turned over, the mechanisms controlling fat cell number in WAT …
adipocytes are continuously turned over, the mechanisms controlling fat cell number in WAT …
Revisiting the regulatory roles of the TGF-β family of cytokines
K Fujio, T Komai, M Inoue, K Morita, T Okamura… - Autoimmunity …, 2016 - Elsevier
TGF-β family members are multipotent cytokines that are involved in many cellular
processes, including cell differentiation, organ development, wound healing and immune …
processes, including cell differentiation, organ development, wound healing and immune …
[HTML][HTML] Interleukin-1 and transforming growth factor beta: commonly opposing, but sometimes supporting, master regulators of the corneal wound healing response to …
SE Wilson - Investigative ophthalmology & visual science, 2021 - arvojournals.org
Purpose: Interleukin (IL)-1α/IL-1β and transforming growth factor (TGF) β1/TGFβ2 have both
been promoted as “master regulators” of the corneal wound healing response due to the …
been promoted as “master regulators” of the corneal wound healing response due to the …
Biological activity differences between TGF-β1 and TGF-β3 correlate with differences in the rigidity and arrangement of their component monomers
TGF-β1,-β2, and-β3 are small, secreted signaling proteins. They share 71–80% sequence
identity and signal through the same receptors, yet the isoform-specific null mice have …
identity and signal through the same receptors, yet the isoform-specific null mice have …