Pseudomonas aeruginosa is a bacterial pathogen associated with a wide range of infections
and utilizes several strategies to establish and maintain infection including biofilm …

The use and misuse of antibiotics have made antibiotic-resistant bacteria widespread
nowadays, constituting one of the most relevant challenges for human health at present …

Pseudomonas is a bacterial genus, with a bona fide environmental habitat that comprises
different species, some of them causing diseases in humans and plants, as well as some …

The human opportunistic pathogen Pseudomonas aeruginosa orchestrates the expression
of many genes in a cell density-dependent manner by using quorum sensing (QS). Two acyl …

Allogeneous selection occurs when an antibiotic selects for resistance to more advanced
members of the same family. The mechanisms of allogenous selection are (a) collateral …

Simple Summary Infectious bacteria (microbes) are able to evolve to become resistant to
antibiotics (develop antimicrobial resistance, or AMR). Resistant microbes are harder to …

Multidrug efflux pumps are ancient elements encoded in every genome, from bacteria to
humans. In bacteria, in addition to antibiotics, efflux pumps extrude a wide range of …

Low antibiotic concentrations present in natural environments are a severe and often
neglected threat to public health. Even if they are present below their MICs, they may select …

The identification of targets whose inactivation increases the activity of antibiotics helps to
fight antibiotic resistance. Previous work showed that a transposon-insertion mutant in the …

Pseudomonas aeruginosa (PA), a non–lactose-fermenting gram-negative bacillus, is a
common cause of nosocomial infections in critically ill or debilitated patients, particularly …