Sepsis: network pathophysiology and implications for early diagnosis

J Arora, AA Mendelson… - American Journal of …, 2023 - journals.physiology.org
Sepsis, a medical emergency, is the overwhelming host response to infection leading to
organ failure. The pathophysiology of this heterogeneous disease includes an inflammatory …

The effect of sepsis on the erythrocyte

RM Bateman, MD Sharpe, M Singer… - International journal of …, 2017 - mdpi.com
Sepsis induces a wide range of effects on the red blood cell (RBC). Some of the effects
including altered metabolism and decreased 2, 3-bisphosphoglycerate are preventable with …

Impact of COVID‐19 on red blood cell rheology.

C Renoux, R Fort, E Nader, C Boisson… - British journal of …, 2021 - search.ebscohost.com
Abstract Keywords: COVID-19; red blood cell; deformability; aggregation; blood viscosity EN
COVID-19 red blood cell deformability aggregation blood viscosity e108 e111 4 02/17/21 …

Effects of nitric oxide on red blood cell deformability

M Bor-Kucukatay, RB Wenby… - … of physiology-heart …, 2003 - journals.physiology.org
In addition to its known action on vascular smooth muscle, nitric oxide (NO) has been
suggested to have cardiovascular effects via regulation of red blood cell (RBC) …

Human malarial disease: a consequence of inflammatory cytokine release

IA Clark, AC Budd, LM Alleva, WB Cowden - Malaria journal, 2006 - Springer
Malaria causes an acute systemic human disease that bears many similarities, both
clinically and mechanistically, to those caused by bacteria, rickettsia, and viruses. Over the …

Bench-to-bedside review: microvascular dysfunction in sepsis–hemodynamics, oxygen transport, and nitric oxide

RM Bateman, MD Sharpe, CG Ellis - Critical care, 2003 - Springer
The microcirculation is a complex and integrated system that supplies and distributes
oxygen throughout the tissues. The red blood cell (RBC) facilitates convective oxygen …

The prognostic value of muscle StO2 in septic patients

J Creteur, T Carollo, G Soldati, G Buchele… - Intensive care …, 2007 - Springer
Objective: To quantify sepsis-induced alterations in changes in muscle tissue oxygenation
(StO 2) after an ischemic challenge using near-infrared spectroscopy (NIRS), and to test the …

Metabolic influences modulating erythrocyte deformability and eryptosis

JF Brun, E Varlet-Marie, J Myzia… - Metabolites, 2021 - mdpi.com
Many factors in the surrounding environment have been reported to influence erythrocyte
deformability. It is likely that some influences represent reversible changes in erythrocyte …

Red blood cell rheology in sepsis

M Piagnerelli, KZ Boudjeltia, M Vanhaeverbeek… - Applied Physiology in …, 2009 - Springer
Abstract Changes in red blood cell (RBC) function can contribute to alterations in
microcirculatory blood flow and cellular dysoxia in sepsis. Decreases in RBC and neutrophil …

The pathophysiology of falciparum malaria

IA Clark, WB Cowden - Pharmacology & therapeutics, 2003 - Elsevier
Falciparum malaria is a complex disease with no simple explanation, affecting organs where
the parasite is rare as well as those organs where it is more common. We continue to argue …