Nicotiana benthamiana: Its History and Future as a Model for Plant–Pathogen Interactions

MM Goodin, D Zaitlin, RA Naidu… - Molecular plant …, 2008 - Am Phytopath Society
Nicotiana benthamiana is the most widely used experimental host in plant virology, due
mainly to the large number of diverse plant viruses that can successfully infect it …

New dimensions for VIGS in plant functional genomics

M Senthil-Kumar, KS Mysore - Trends in plant science, 2011 - cell.com
Virus-induced gene silencing (VIGS) is an efficient tool for gene function studies. It has been
used to perform both forward and reverse genetics to identify plant genes involved in several …

Tobacco rattle virus–based virus-induced gene silencing in Nicotiana benthamiana

M Senthil-Kumar, KS Mysore - Nature protocols, 2014 - nature.com
Tobacco rattle virus (TRV)-based virus-induced gene silencing (VIGS) is widely used in
various plant species to downregulate the expression of a target plant gene. TRV is a …

RNA virus interference via CRISPR/Cas13a system in plants

R Aman, Z Ali, H Butt, A Mahas, F Aljedaani, MZ Khan… - Genome biology, 2018 - Springer
Background CRISPR/Cas systems confer immunity against invading nucleic acids and
phages in bacteria and archaea. CRISPR/Cas13a (known previously as C2c2) is a class 2 …

Validation of Reference Genes for Gene Expression Studies in Virus-Infected Nicotiana benthamiana Using Quantitative Real-Time PCR

D Liu, L Shi, C Han, J Yu, D Li, Y Zhang - 2012 - journals.plos.org
Nicotiana benthamiana is the most widely-used experimental host in plant virology. The
recent release of the draft genome sequence for N. benthamiana consolidates its role as a …

CRISPR/Cas9-mediated genome editing and gene replacement in plants: transitioning from lab to field

SM Schaeffer, PA Nakata - Plant Science, 2015 - Elsevier
The CRISPR/Cas9 genome engineering system has ignited and swept through the scientific
community like wildfire. Owing largely to its efficiency, specificity, and flexibility, the …

VIGS–genomics goes functional

A Becker, M Lange - Trends in plant science, 2010 - cell.com
Genome and EST sequencing projects generate a wealth of sequence information for
agronomically and phylogenetically important plant species of which the majority is difficult …

The SGN VIGS tool: user-friendly software to design virus-induced gene silencing (VIGS) constructs for functional genomics

N Fernandez-Pozo, HG Rosli, GB Martin, LA Mueller - Molecular plant, 2015 - cell.com
Virus-induced gene silencing (VIGS) is a fast and powerful method to study gene function in
plants (Burch-Smith et al., 2004). It is based on plant defense mechanisms against viral …

CRISPR guides induce gene silencing in plants in the absence of Cas

VK Sharma, S Marla, W Zheng, D Mishra, J Huang… - Genome Biology, 2022 - Springer
Abstract Background RNA-targeting CRISPR-Cas can provide potential advantages over
DNA editing, such as avoiding pleiotropic effects of genome editing, providing precise …

Virus-induced gene silencing (VIGS) in Nicotiana benthamiana and tomato

AC Velásquez, S Chakravarthy… - Journal of visualized …, 2009 - pmc.ncbi.nlm.nih.gov
RNA interference (RNAi) is a highly specific gene-silencing phenomenon triggered by
dsRNA1. This silencing mechanism uses two major classes of RNA regulators: microRNAs …