Progress in sequencing technologies and clinical experiments has revolutionized
immunotherapy on solid and hematologic malignancies. However, the benefits of …

Spatial properties of tumour growth have profound implications for cancer progression,
therapeutic resistance and metastasis. Yet, how spatial position governs tumour cell division …

Molecular subtypes of colorectal cancer (CRC) are currently identified via the snapshot
transcriptional profiles, largely ignoring the dynamic changes of gene expressions …

Purpose This study aims to assess the diagnostic value of ultrasound habitat sub-region
radiomics feature parameters using a fully connected neural networks (FCNN) combination …

肿瘤本身是一个复杂的微生态系统, 存在复杂时空动态和多维度的互作关系,
其超乎想象的异质性与演化能力已经超出了传统肿瘤医学的认知. 如何系统性地从物质, 能量 …

In growing cell populations such as tumours, mutations can serve as markers that allow
tracking the past evolution from current samples. The genomic analyses of bulk samples and …