The founding in 1965 of what is now called the Cambridge Structural Database (CSD) has
reaped dividends in numerous and diverse areas of chemical research. Each of the million …

1.1. Influence of the Composition Coordination polymers or MOFs (metalÀorganic
frameworks) are the latest class of ordered porous solids. 1À5Since their discovery in 1989 …

This Tutorial Review, aimed at both the novice and the seasoned solid-state chemist,
provides a succinct overview of key findings that have, over the last half century, advanced …

In recent years cocrystal formation has emerged as a viable strategy towards improving the
solubility and bioavailability of poorly soluble drugs. In this review the success of numerous …

Salt and cocrystal formation are the most commonly used method of increasing solubility
and dissolution rate of pharmaceutical compounds, and are of particular interest for …

Calculated gas phase molecular electrostatic potential surfaces have been used to identify
sets of H-bond donor and H-bond acceptor sites that describe the possible intermolecular …

Coordination complexes (including discrete coordination complexes and coordination
polymers) have demonstrated excellent performance in drug delivery. This review outlines …

Crystal structure prediction for organic molecules requires both the fast assessment of
thousands to millions of crystal structures and the greatest possible accuracy in their relative …

Design and synthesis of pharmaceutical cocrystals have received great interest in recent
years. Cocrystallization of drug substances offers a tremendous opportunity for the …

Crystal structure prediction (CSP) studies are not limited to being a search for the most
thermodynamically stable crystal structure, but play a valuable role in understanding …