Synthetic glycans to improve current glycoconjugate vaccines and fight antimicrobial resistance
L Del Bino, KE Østerlid, DY Wu, F Nonne… - Chemical …, 2022 - ACS Publications
Antimicrobial resistance (AMR) is emerging as the next potential pandemic. Different
microorganisms, including the bacteria Acinetobacter baumannii, Clostridioides difficile …
microorganisms, including the bacteria Acinetobacter baumannii, Clostridioides difficile …
Management of infants at risk for group B streptococcal disease
KM Puopolo, R Lynfield, JJ Cummings, I Hand… - …, 2019 - publications.aap.org
Group B streptococcal (GBS) infection remains the most common cause of neonatal early-
onset sepsis and a signiicant cause of late-onset sepsis among young infants …
onset sepsis and a signiicant cause of late-onset sepsis among young infants …
Potential for maternally administered vaccine for infant group B streptococcus
SA Madhi, AS Anderson, J Absalon… - … England Journal of …, 2023 - Mass Medical Soc
Background Natural history studies have correlated serotype-specific anti–capsular
polysaccharide (CPS) IgG in newborns with a reduced risk of group B streptococcal disease …
polysaccharide (CPS) IgG in newborns with a reduced risk of group B streptococcal disease …
Estimates of the burden of group B streptococcal disease worldwide for pregnant women, stillbirths, and children
AC Seale, F Bianchi-Jassir, NJ Russell… - Clinical infectious …, 2017 - academic.oup.com
Background We aimed to provide the first comprehensive estimates of the burden of group B
Streptococcus (GBS), including invasive disease in pregnant and postpartum women, fetal …
Streptococcus (GBS), including invasive disease in pregnant and postpartum women, fetal …
Group B streptococcal colonization, molecular characteristics, and epidemiology
S Shabayek, B Spellerberg - Frontiers in microbiology, 2018 - frontiersin.org
Streptococcus agalactiae or group B streptococcus (GBS) is a leading cause of serious
neonatal infections. GBS is an opportunistic commensal constituting a part of the intestinal …
neonatal infections. GBS is an opportunistic commensal constituting a part of the intestinal …
Global, regional, and national burden of meningitis, 1990–2016: a systematic analysis for the Global Burden of Disease Study 2016
JR Zunt, NJ Kassebaum, N Blake, L Glennie… - The Lancet …, 2018 - thelancet.com
Background Acute meningitis has a high case-fatality rate and survivors can have severe
lifelong disability. We aimed to provide a comprehensive assessment of the levels and …
lifelong disability. We aimed to provide a comprehensive assessment of the levels and …
Safety and immunogenicity of a novel hexavalent group B streptococcus conjugate vaccine in healthy, non-pregnant adults: a phase 1/2, randomised, placebo …
J Absalon, N Segall, SL Block, KJ Center… - The Lancet Infectious …, 2021 - thelancet.com
Summary Background Group B streptococcus (GBS) is a major cause of invasive disease in
young infants. Infants born to women with sufficient pre-existing anti-GBS capsular IgG …
young infants. Infants born to women with sufficient pre-existing anti-GBS capsular IgG …
Epidemiology of invasive group B streptococcal infections among nonpregnant adults in the United States, 2008-2016
LKF Watkins, L McGee, SJ Schrag, B Beall… - JAMA internal …, 2019 - jamanetwork.com
Importance Group BStreptococcus (GBS) is an important cause of invasive bacterial
disease. Previous studies have shown a substantial and increasing burden of GBS …
disease. Previous studies have shown a substantial and increasing burden of GBS …
Impact of intrapartum and postnatal antibiotics on the gut microbiome and emergence of antimicrobial resistance in infants
T Tapiainen, P Koivusaari, L Brinkac, HA Lorenzi… - Scientific reports, 2019 - nature.com
Abstract Altogether, 20–30% of women receive intrapartum antibiotic prophylaxis (IAP) to
prevent sepsis in infants and 2–5% of newborn infants receive antibiotics due to suspected …
prevent sepsis in infants and 2–5% of newborn infants receive antibiotics due to suspected …
The Impact of IgG transplacental transfer on early life immunity
Pediatric vaccines have significantly reduced infectious disease–related infant mortality, but
as protective immunity often requires several infant vaccine doses, maternally acquired Abs …
as protective immunity often requires several infant vaccine doses, maternally acquired Abs …