Ice inhibition for cryopreservation: materials, strategies, and challenges

T Chang, G Zhao - Advanced Science, 2021 - Wiley Online Library
Cryopreservation technology has developed into a fundamental and important supporting
method for biomedical applications such as cell‐based therapeutics, tissue engineering …

The formation and control of ice crystal and its impact on the quality of frozen aquatic products: A review

M Tan, J Mei, J Xie - Crystals, 2021 - mdpi.com
Although freezing has been used to delay the deterioration of product quality and extend its
shelf life, the formation of ice crystals inevitably destroys product quality. This …

Antifreeze polysaccharides from wheat bran: The structural characterization and antifreeze mechanism

T Yang, Y Zhang, L Guo, D Li, A Liu, M Bilal… - …, 2024 - ACS Publications
Exploring a novel natural cryoprotectant and understanding its antifreeze mechanism allows
the rational design of future sustainable antifreeze analogues. In this study, various …

The atomistic details of the ice recrystallisation inhibition activity of PVA

F Bachtiger, TR Congdon, C Stubbs, MI Gibson… - Nature …, 2021 - nature.com
Understanding the ice recrystallisation inhibition (IRI) activity of antifreeze biomimetics is
crucial to the development of the next generation of cryoprotectants. In this work, we bring …

Control of ice crystal nucleation and growth during the food freezing process

G Jia, Y Chen, AD Sun, V Orlien - Comprehensive Reviews in …, 2022 - Wiley Online Library
Freezing can maintain a low‐temperature environment inside food, reducing water activity
and preventing microorganism growth. However, when ice crystals are large, present in high …

Nanoscopy of single antifreeze proteins reveals that reversible ice binding is sufficient for ice recrystallization inhibition but not thermal hysteresis

RP Tas, MMRM Hendrix… - Proceedings of the …, 2023 - National Acad Sciences
Antifreeze proteins (AFPs) bind ice to reduce freezing temperatures and arrest ice crystal
ripening, making AFPs essential for the survival of many organisms in ice-laden …

Inhibition of ice recrystallization by tamarind (Tamarindus indica L.) seed polysaccharide and molecular weight effects

X Sun, R Guo, Y Kou, H Song, T Zhan, J Wu… - Carbohydrate …, 2023 - Elsevier
This study aimed to investigate the inhibition effects of tamarind seed polysaccharide (TSP)
on ice recrystallization and to figure out its possible molecular weight-dependent effects …

Dimethyl sulfoxide-free cryopreservation for cell therapy: A review

L Weng, PR Beauchesne - Cryobiology, 2020 - Elsevier
Cell-based therapeutics promise to transform the treatment of a wide range of diseases
including cancer, genetic and degenerative disorders, or severe injuries. Many of the …

Metal–organic framework nanoparticle-assisted cryopreservation of red blood cells

W Zhu, J Guo, JO Agola, JG Croissant… - Journal of the …, 2019 - ACS Publications
The development of hybrid nanomaterials mimicking antifreeze proteins that can
modulate/inhibit the growth of ice crystals for cell/tissue cryopreservation has attracted …

Slow propagation of ice binding limits the ice-recrystallization inhibition efficiency of PVA and other flexible polymers

PM Naullage, V Molinero - Journal of the American Chemical …, 2020 - ACS Publications
Ice recrystallization inhibitors (IRI) are of critical importance in biology, cryopreservation of
cells and organs, and frozen foods. Antifreeze glycoproteins (AFGPs) are the most potent …