Animal models of traumatic brain injury and assessment of injury severity

X Ma, A Aravind, BJ Pfister, N Chandra… - Molecular neurobiology, 2019 - Springer
Traumatic brain injury (TBI) contributes a major cause of death, disability, and mental health
disorders. Most TBI patients suffer long-term post-traumatic stress disorder, cognitive …

[HTML][HTML] Traumatic brain injury: Mechanisms, manifestations, and visual sequelae

SH Rauchman, A Zubair, B Jacob… - Frontiers in …, 2023 - frontiersin.org
Traumatic brain injury (TBI) results when external physical forces impact the head with
sufficient intensity to cause damage to the brain. TBI can be mild, moderate, or severe and …

Rapid point-of-care detection and classification of direct-acting oral anticoagulants with the TEG 6s: Implications for trauma and acute care surgery

JD Dias, CG Lopez-Espina, J Ippolito… - Journal of Trauma …, 2019 - journals.lww.com
BACKGROUND The trauma patient on direct oral anticoagulant (DOAC) therapy preinjury
presents a challenge in trauma and acute care surgery. Our understanding of these patients …

[HTML][HTML] Rates of intracranial hemorrhage in mild head trauma patients presenting to emergency department and their management: a comparison of direct oral …

G Savioli, IF Ceresa, S Luzzi, C Gragnaniello… - Medicina, 2020 - mdpi.com
Background and objectives: Anticoagulants are thought to increase the risks of traumatic
intracranial injury and poor clinical outcomes after blunt head trauma. The safety of using …

Effect of preinjury oral anticoagulants on outcomes following traumatic brain injury from falls in older adults

JP Hecht, ZJ LaDuke, AH Cain‐Nielsen… - … : The Journal of …, 2020 - Wiley Online Library
Background Warfarin has been the oral anticoagulant of choice for the treatment of
thromboembolic disease. However, upward of 50% of all new anticoagulant prescriptions …

Coagulopathy and progression of intracranial hemorrhage in traumatic brain injury: mechanisms, impact, and therapeutic considerations

M Maegele - Neurosurgery, 2021 - journals.lww.com
BACKGROUND Traumatic brain injury (TBI) remains one of the most challenging health and
socioeconomic problems of our times. Clinical courses may be complicated by hemostatic …

[HTML][HTML] Acute Haemostatic Depletion and Failure in Patients with Traumatic Brain Injury (TBI): Pathophysiological and Clinical Considerations

F Kockelmann, M Maegele - Journal of Clinical Medicine, 2023 - mdpi.com
Background: Because of the aging population, the number of low falls in elderly people with
pre-existing anticoagulation is rising, often leading to traumatic brain injury (TBI) with a …

[HTML][HTML] Impact of preinjury antithrombotic therapy on 30–day mortality in older patients hospitalized with traumatic brain injury (TBI)

P Rønning, E Helseth, O Skaansar, C Tverdal… - Frontiers in …, 2021 - frontiersin.org
Objective: Elderly patients are frequently in need of antithrombotic therapy for reducing
thrombotic events. The association between antithrombotic drugs and survival after …

[HTML][HTML] Management of Traumatic Brain Injury in Patients with DOAC Therapy–Are the “New” Oral Anticoagulants Really Safer?

A Antoni, L Wedrich, M Schauperl, L Höchtl-Lee… - Journal of Clinical …, 2022 - mdpi.com
(1) Background: In recent years,“new” direct oral anticoagulants (DOAC) have gradually
replaced other antithrombotic therapies. The international literature agrees on the increased …

Predictors of post-traumatic complication of mild brain injury in anticoagulated patients: DOACs are safer than VKAs

A Cipriano, N Park, A Pecori, A Bionda… - Internal and Emergency …, 2021 - Springer
Although mild traumatic brain injury (MTBI) in people on oral anticoagulant treatment (OAT)
is a frequent challenge for Emergency Department (ED), strong guidelines …