Paediatric melanoma is rare and challenging to diagnose. The three subtypes are Spitzoid
melanoma, melanoma arising in a congenital melanocytic nevus, and conventional (also …

Purpose: Ipilimumab is a first-in-class immune checkpoint inhibitor approved for treatment of
metastatic melanoma but not studied in children until this phase I protocol. Experimental …

The purpose of this review is to outline recent advancements in diagnosis, treatment, and
prevention of pediatric melanoma. Despite the recent decline in incidence, it continues to be …

Background We postulated that the worse prognosis of melanoma with advancing age
reflected more aggressive tumor biology and that in younger patients the prognosis would …

Purpose We have previously reported that older patients with clinical stage I and II primary
cutaneous. Melanoma had lower survival rates compared to younger patients. We …

Death due to melanoma in childhood (up to 20 y of age) is a rare event, with an average of
18 cases reported annually in the United States. In this study we evaluated 2 subgroups of …

BACKGROUND The management of pediatric melanoma (PM) has largely been
extrapolated from adult data. However, the behavior of PM appears to differ from its adult …

Background Diagnosis and proper management of atypical Spitz tumors in pediatric age are
still controversial. Objective We sought to investigate the clinicopathological and molecular …

Background Studies have demonstrated a higher rate of nodal metastases in melanoma of
childhood, but there is controversy about the overall prognosis relative to adults. We …

Background Studies suggest that the biology of pediatric and adolescent melanoma differs
from that of adult disease. We report the largest series to date examining the natural history …