Key Points Frailty in Older Adults Assessing frailty enables clinicians to predict the outcomes
and risks of health conditions, target the delivery of evidence-based interventions, and tailor …

With the aging of the world's population, a large proportion of patients seen in
cardiovascular practice are older adults, but many patients also exhibit signs of physical …

Introduction The prevalence of frailty at population level is unclear. We examined this in
population-based studies, investigating sources of heterogeneity. Methods PubMed …

Background At the beginning of June 2020, there were nearly 7 million reported cases of
coronavirus disease 2019 (COVID-19) worldwide and over 400,000 deaths in people with …

Frailty in aging marks a state of decreased reserves resulting in increased vulnerability to
adverse outcomes when exposed to stressors. This Perspective synthesizes the evidence …

Frailty is an emerging global health burden, with major implications for clinical practice and
public health. The prevalence of frailty is expected to rise alongside rapid growth in the …

Free radicals and oxidants are involved in physiological signaling pathways, although an
imbalance between pro-oxidant and anti-oxidant systems in favor of the former leads to …

The aging process is characterized by the presence of high interindividual variation between
individuals of the same chronical age prompting a search for biomarkers that capture this …

“Frailty” is a term used to refer to a state characterized by enhanced vulnerability to, and
impaired recovery from, stressors compared with a nonfrail state, which is increasingly …

Objective The task force of the International Conference of Frailty and Sarcopenia Research
(ICFSR) developed these clinical practice guidelines to overview the current evidence-base …