Biologically active dihydropyrimidones of the Biginelli-type—a literature survey

CO Kappe - European journal of medicinal chemistry, 2000 - Elsevier
In 1893, the synthesis of functionalized 3, 4-dihydropyrimidin-2 (1H)-ones (DHPMs) via three-
component condensation reaction of an aromatic aldehyde, urea and ethyl acetoacetate …

Arylglyoxals in synthesis of heterocyclic compounds

B Eftekhari-Sis, M Zirak, A Akbari - Chemical reviews, 2013 - ACS Publications
Heterocycles are an extraordinarily important class of compounds, making up more than half
of all known organic compounds. Heterocycles are present in a wide variety of drugs, most …

A Reexamination of the Mechanism of the Biginelli Dihydropyrimidine Synthesis. Support for an N-Acyliminium Ion Intermediate1

CO Kappe - The Journal of organic chemistry, 1997 - ACS Publications
The mechansim of the three-component Biginelli dihydropyrimidine synthesis was
reinvestigated using 1H and 13C NMR spectroscopy. Condensation of benzaldehyde, ethyl …

Lanthanide triflate catalyzed Biginelli reaction. One-pot synthesis of dihydropyrimidinones under solvent-free conditions

Y Ma, C Qian, L Wang, M Yang - Journal of Organic …, 2000 - organic-chemistry.org
Abstract By using Yb (OTf) 3 as a catalyst and under solvent-free reaction conditions, the
yields of the one-pot Biginelli reaction can be increased while the reaction time was …

Ionic liquids catalyzed Biginelli reaction under solvent-free conditions

J Peng, Y Deng - Tetrahedron Letters, 2001 - Elsevier
3, 4-Dihydropyrimidin-2 (1H)-ones were synthesised in high yields by one-pot three-
component Biginelli condensation in the presence of room temperature ionic liquids such as …

A revision of the Biginelli reaction under solid acid catalysis. Solvent-free synthesis of dihydropyrimidines over montmorillonite KSF

F Bigi, S Carloni, B Frullanti, R Maggi, G Sartori - Tetrahedron Letters, 1999 - Elsevier
The reaction of aldehydes, β-dicarbonyl compounds and urea (Biginelli reaction) has been
performed over solid acid catalysis, under solventless conditions or in water affording …

Zirconium (IV) chloride catalyzed one-pot synthesis of 3, 4-dihydropyrimidin-2 (1H)-ones

CV Reddy, M Mahesh, PVK Raju, TR Babu… - Tetrahedron …, 2002 - Elsevier
Zirconium(IV) chloride catalyzed one-pot synthesis of 3,4-dihydropyrimidin-2(1H)-ones -
ScienceDirect Skip to main contentSkip to article Elsevier logo Journals & Books Search …

Magnetic Fe3O4 nanoparticles: Efficient and recoverable nanocatalyst for the synthesis of polyhydroquinolines and Hantzsch 1, 4-dihydropyridines under solvent-free …

M Nasr-Esfahani, SJ Hoseini… - Journal of Molecular …, 2014 - Elsevier
A green approach for efficient and rapid synthesis of biologically active substituted Hantzsch
1, 4-dihydropyridine and polyhydroquinoline derivatives using magnetic Fe 3 O 4 …

Mn (OAc) 3· 2H2O-mediated three-component, one-pot, condensation reaction: an efficient synthesis of 4-aryl-substituted 3, 4-dihydropyrimidin-2-ones

KA Kumar, M Kasthuraiah, CS Reddy, CD Reddy - Tetrahedron Letters, 2001 - Elsevier
Mn(OAc)3·2H2O-mediated three-component, one-pot, condensation reaction: an efficient
synthesis of 4-aryl-substituted 3,4-dihydropyrimidin-2-ones - ScienceDirect Skip to main …

[HTML][HTML] An efficient synthesis of 3, 4-dihydropyrimidin-2-ones catalyzed by NH2SO3H under ultrasound irradiation

JT Li, JF Han, JH Yang, TS Li - Ultrasonics Sonochemistry, 2003 - Elsevier
An efficient synthesis of 3,4-dihydropyrimidin-2-ones catalyzed by NH2SO3H under ultrasound
irradiation - ScienceDirect Skip to main contentSkip to article Elsevier logo Journals & Books …