Gelsolin, an actin-depolymerizing protein expressed both in extracellular fluids and in the
cytoplasm of a majority of human cells, has been recently implicated in a variety of both …

Pancreatic cancer is currently the most lethal tumor entity and case numbers are rising. It will
soon be the second most frequent cause of cancer-related death in the Western world …

Mass spectrometry-based proteomic technique has become indispensable in current
exploration of complex and dynamic biological processes. Instrument development has …

Pancreatic ductal adenocarcinoma (PDAC) has prominent extracellular matrix (ECM) that
compromises treatments yet cannot be nonselectively disrupted without adverse …

The discovery of proper molecular signature from OMIC data is indispensable for
determining biological state, physiological condition, disease etiology, and therapeutic …

Exosomes are cell-derived, phospholipid bilayer-enclosed vesicles that play important roles
in intercellular interactions and regulate many biological processes. Accumulating evidence …

Simple Summary The traditional approach in identifying cancer related protein biomarkers
has focused on evaluation of a single peptide/protein in tissue or circulation. At best, this …

Over a decade ago, longitudinal multiomics analysis was pioneered for early disease
detection and individually tailored precision health interventions. However, high sample …

Pancreatic adenocarcinoma is one of the most lethal cancers in both men and women, with
a median five-year survival of around 5%. Therefore, pancreatic adenocarcinoma represents …

Colorectal cancer (CRC) is a common malignant neoplasm worldwide. It is important to
identify new biomarkers for the early detection of CRC. In this study, magnetic beads and the …