Immunotherapy has achieved prominent clinical efficacy in combating cancer and has
recently become a mainstream treatment strategy. However, achieving broad efficacy with a …

Cancer is a major public health concern worldwide; it is the second-highest cause of death
in the United States. According to projections of cancer incidence and mortality rates …

Camptothecin, a natural alkaloid, was first isolated from the bark and stem of the
Camptotheca acuminate tree in China. It, along with its analogs, has demonstrated potent …

Aiming toward the development of tailored carrier materials for the cytostatics panobinostat
and imatinib, an amphiphilic block copolymer composed of poly (2-ethyl-2-oxazoline) and a …

Nitric oxide (NO) is a crucial signal molecule closely linked to the biological immune
response, especially in macrophage polarization. When activated, macrophages enter a pro …

Arsenic trioxide (ATO) is highly effective for acute promyelocytic leukemia but has limited
potency in solid tumors. Mitigating the systemic toxicity of ATO while enhancing its efficacy in …

Therapeutic approaches for triple-negative breast cancer (TNBC) have been continuously
advancing, but inadequate control over release behavior, insufficient tumor selectivity, and …

A pioneering approach in the domain of transdermal drug delivery systems (TDDS) is
introduced by using microneedles (MNs) fabricated from an amorphous solid dispersion …

Triple‐negative breast cancer (TNBC) is notoriously difficult to treat due to the lack of
targetable receptors and sometimes poor response to chemotherapy. The transforming …

Here, we introduce a pioneering approach in the domain of transdermal drug delivery
systems (TDDS) by using microneedles (MNs) fabricated from amorphous solid dispersion …