Chlamydiaceae: Diseases in Primary Hosts and Zoonosis

HC Cheong, CYQ Lee, YY Cheok, GMY Tan, CY Looi… - Microorganisms, 2019 - mdpi.com
Bacteria of the Chlamydiaceae family are a type of Gram-negative microorganism typified by
their obligate intracellular lifestyle. The majority of the members in the Chlamydiaceae family …

The functions and therapeutic potential of heat shock proteins in inflammatory bowel disease—an update

A Hoter, HY Naim - International journal of molecular sciences, 2019 - mdpi.com
Inflammatory bowel disease (IBD) is a multifactorial human intestinal disease that arises
from numerous, yet incompletely defined, factors. Two main forms, Crohn's disease (CD) …

Hsp60 as a novel target in IBD management: a prospect

F Cappello, M Mazzola, A Jurjus, MN Zeenny… - Frontiers in …, 2019 - frontiersin.org
Inflammatory bowel disease (IBD) encompasses various pathological conditions similar but
distinct that share a multifactorial etiology, including involvement of the intestinal barrier …

Chlamydia trachomatis plasmid-encoding Pgp3 protein induces secretion of distinct inflammatory signatures from HeLa cervical epithelial cells

HC Cheong, YY Cheok, YT Chan, TF Tang… - BMC microbiology, 2023 - Springer
Abstract Background Genital Chlamydia trachomatis infection is the most common bacterial
sexual transmitted disease that causes severe complications including pelvic inflammatory …

HSP60 Regulates Monosodium Urate Crystal‐Induced Inflammation by Activating the TLR4‐NF‐κB‐MyD88 Signaling Pathway and Disrupting Mitochondrial Function

Q Huang, W Gao, H Mu, T Qin, F Long… - Oxidative Medicine …, 2020 - Wiley Online Library
Acute gout is an inflammatory response induced by monosodium urate (MSU) crystals.
HSP60 is a highly conserved stress protein that acts as a cellular “danger” signal for immune …

Gut microbiota changes in horses with Chlamydia

Y Jin, W Li, X Ba, Y Li, Y Wang, H Zhang, Z Li, J Zhou - BMC microbiology, 2023 - Springer
Background Zoonotic diseases pose a significant threat to public health. Chlamydia, as an
intracellular pathogen, can colonize the intestinal tract of humans and animals, changing the …

Molecular mechanisms in chaperonopathies: clues to understanding the histopathological abnormalities and developing novel therapies

AJL Macario, EC de Macario - The Journal of Pathology, 2020 - Wiley Online Library
Molecular chaperones, many of which are heat shock proteins (Hsps), are components of
the chaperoning system and when defective can cause disease, the chaperonopathies …

Insights Into Host Cell Cytokines in Chlamydia Infection

W Xiang, N Yu, A Lei, X Li, S Tan, L Huang… - Frontiers in …, 2021 - frontiersin.org
Chlamydial infection causes a number of clinically relevant diseases and induces significant
morbidity in humans. Immune and inflammatory responses contribute to both the clearance …

Plant flavonoids bioavailability in vivo and mechanisms of benefits on chronic kidney disease: A comprehensive review

Y Lin, J Fang, Z Zhang, MA Farag, Z Li, P Shao - Phytochemistry Reviews, 2023 - Springer
Chronic kidney disease is a syndrome defined as the continuous change of renal structure,
considered as one of the top 10 causes of death worldwide. In the past few decades, dietary …

Chronic Inflammatory Diseases at Secondary Sites Ensuing Urogenital or Pulmonary Chlamydia Infections

YY Cheok, CYQ Lee, HC Cheong, CY Looi, WF Wong - Microorganisms, 2020 - mdpi.com
Chlamydia trachomatis and C. pneumoniae are members of the Chlamydiaceae family of
obligate intracellular bacteria. The former causes diseases predominantly at the mucosal …