Mechanisms underlying the initiation of parturition remain unclear. Throughout most of
pregnancy, uterine quiescence is maintained by elevated progesterone acting through …

A panic response is an adaptive response to deal with an imminent threat and consists of an
integrated pattern of behavioral (aggression, fleeing, or freezing) and increased …

It has been postulated that during human fetal development, all cells of the lung epithelium
derive from embryonic, endodermal, NK2 homeobox 1–expressing (NKX2-1+) precursor …

Preclinical and some clinical studies suggest a relationship between perturbation in
magnesium (Mg2+) homeostasis and pathological anxiety, although the underlying …

Corticotropin releasing hormone (CRH) is essential for stress adaptation by mediating
hypothalamic–pituitary–adrenal (HPA) axis, behavioral and autonomic responses to stress …

Corticotropin-releasing hormone (CRH) is a central regulator of the hormonal stress
response, causing stimulation of corticotropin and glucocorticoid secretion. CRH is also …

Hypothalamic nuclei, including the anterior periventricular (aPV), paraventricular (PVN), and
supraoptic (SON) nuclei strongly express the homeobox gene Orthopedia (Otp) during …

The steroid hormones progesterone (P4) and estradiol-17β (E2), produced by the placenta
in humans and the ovaries in rodents, serve crucial roles in the maintenance of pregnancy …

The vertebrate corticosteroid stress response is highly conserved and a key function is to
restore homeostasis by mobilizing and reallocating energy stores. This process is primarily …

Female mice deficient in steroid 5α-reductase type 1 have a decreased litter size. The
average litter in homozygous deficient females is 2.7 pups vs. 8.0 pups in wild type controls …