DNA methylation profiles in cancer diagnosis and therapeutics
Y Pan, G Liu, F Zhou, B Su, Y Li - Clinical and experimental medicine, 2018 - Springer
Cancer initiation and proliferation is regulated by both epigenetic and genetic events with
epigenetic modifications being increasingly identified as important targets for cancer …
epigenetic modifications being increasingly identified as important targets for cancer …
DNA methylation-based testing in liquid biopsies as detection and prognostic biomarkers for the four major cancer types
Lung, breast, colorectal, and prostate cancers are the most incident worldwide. Optimal
population-based cancer screening methods remain an unmet need, since cancer detection …
population-based cancer screening methods remain an unmet need, since cancer detection …
DNA methylation profiling in the clinic: applications and challenges
H Heyn, M Esteller - Nature Reviews Genetics, 2012 - nature.com
Abstract Knowledge of epigenetic alterations in disease is rapidly increasing owing to the
development of genome-wide techniques for their identification. The ever-growing number …
development of genome-wide techniques for their identification. The ever-growing number …
Point-of-care cancer diagnostic devices: From academic research to clinical translation
L Syedmoradi, ML Norton, K Omidfar - Talanta, 2021 - Elsevier
Early and timely diagnosis of cancer plays a decisive role in appropriate treatment and
improves clinical outcomes, improving public health. Significant advances in biosensor …
improves clinical outcomes, improving public health. Significant advances in biosensor …
Cancer epigenetic biomarkers in liquid biopsy for high incidence malignancies
C Palanca-Ballester, A Rodriguez-Casanova, S Torres… - Cancers, 2021 - mdpi.com
Simple Summary Apart from genetic changes, cancer is characterized by epigenetic
alterations, which indicate modifications in the DNA (such as DNA methylation) and histones …
alterations, which indicate modifications in the DNA (such as DNA methylation) and histones …
Glycans as biomarkers in prostate cancer
Prostate cancer is the most commonly diagnosed malignancy in men, claiming over 350,000
lives worldwide annually. Current diagnosis relies on prostate-specific antigen (PSA) testing …
lives worldwide annually. Current diagnosis relies on prostate-specific antigen (PSA) testing …
[HTML][HTML] The importance of DNA methylation in prostate cancer development
After briefly reviewing the nature of DNA methylation, its general role in cancer and the tools
available to interrogate it, we consider the literature surrounding DNA methylation as …
available to interrogate it, we consider the literature surrounding DNA methylation as …
Epigenetic modifications in prostate cancer
M Sugiura, H Sato, M Kanesaka… - … Journal of Urology, 2021 - Wiley Online Library
Prostate cancer is a major cause of cancer‐related deaths among men worldwide. In
addition to genomic alterations, epigenetic alterations accumulated in prostate cancer have …
addition to genomic alterations, epigenetic alterations accumulated in prostate cancer have …
Cell-free DNA as a diagnostic marker for cancer: current insights
S Salvi, G Gurioli, U De Giorgi, V Conteduca… - Oncotargets and …, 2016 - Taylor & Francis
The increasing knowledge of the molecular pathogenesis of cancer and the rapid
development of new molecular techniques are promoting the study of early molecular …
development of new molecular techniques are promoting the study of early molecular …