Background Gastric cancer imposes a substantial global health burden despite its overall
incidence decrease. A broad spectrum of inherited, environmental and infectious factors …

Gastric cancer, a multifactorial disease, is considered one of the most common malignancies
worldwide. In addition to genetic and environmental risk factors, infectious agents, such as …

Helicobacter pylori (H. pylori) increases production of reactive oxygen species (ROS) and
activates signaling pathways associated with gastric cell invasion, which are mediated by …

Helicobacter pylori (Hp) vacuolating cytotoxin (VacA) is a bacterial exotoxin that enters host
cells and induces mitochondrial dysfunction. However, the extent to which VacA-dependent …

Chronic Helicobacter pylori infection increases the risk of gastric cancer and induction of
hypoxia-induced factor (HIF), which is frequently associated with the development and …

Helicobacter pylori (H. pylori) infection is considered as one of the strongest risk factors for
gastric disorders. Infection triggers several host pathways to elicit inflammation, which further …

Worldwide, gastric cancer (GC) represents the fifth most common cancer for incidence and
the third leading cause of death in developed countries. Despite the development of …

Background Helicobacter pylori (H. pylori) infection has become an international public
health problem, and antibiotic-based triple or quadruple therapy is currently the mainstay of …

Mitochondria is a dynamic organelle of the cell that can regulate and maintain cellular ATP
level, ROS production, calcium signaling and immune response. In order to retain their …

The global rise of antibiotic-resistant strains of Salmonella has necessitated the
development of alternative therapeutic strategies. Recent studies have shown that targeting …