Mitochondria are essential organelles with numerous functions in cellular metabolism and
homeostasis. Most of the> 1,000 different mitochondrial proteins are synthesized as …

Mitochondria are central to energy production, metabolism and signaling, and apoptosis. To
make new mitochondria from preexisting mitochondria, the cell needs to import …

Nearly all mitochondrial proteins are encoded by the nuclear genome and imported into
mitochondria after synthesis on cytosolic ribosomes. These precursor proteins are …

Mitochondria fulfill central functions in bioenergetics, metabolism, and apoptosis. They
import more than 1,000 different proteins from the cytosol. It had been assumed that the …

Abstract About 10% to 15% of the nuclear genes of eukaryotic organisms encode
mitochondrial proteins. These proteins are synthesized in the cytosol and recognized by …

Significance: In the last years, metabolic reprogramming, fluctuations in bioenergetic fuels,
and modulation of oxidative stress became new key hallmarks of tumor development. In …

The chapter provides a review of the state of art of the oxidative phosphorylation system in
mammalian mitochondria. The sections of the paper deal with:(i) the respiratory chain as a …

The architecture of cristae provides a spatial mitochondrial organization that contains
functional respiratory complexes. Several protein components including OPA1 and MICOS …

The biogenesis of mitochondria depends on the import of hundreds of preproteins. N-
terminal matrix-targeting signals (MTSs) direct preproteins to the surface receptors Tom20 …

The development of chloroplasts and the integration of their function within a plant cell rely
on the presence of a complex biochemical machinery located within their limiting envelope …