Better understanding of the immunological components and their interactions necessary to
prevent or control Mycobacterium tuberculosis (Mtb) infection in humans is critical for …

Though primarily enteric pathogens, Salmonellae are responsible for a considerable yet
under-appreciated global burden of invasive disease. In South and South-East Asia, this …

Background The incidence of enteric fever, an invasive bacterial infection caused by
typhoidal Salmonellae (Salmonella enterica serovars Typhi and Paratyphi), is largely …

The advent of new generation TCVs offers us a practical and affordable public-health tool
that–for the first time–can be integrated into routine childhood immunization programmes. In …

Salmonella is a major foodborne pathogen and a leading cause of gastroenteritis in humans
and animals. Salmonella is highly pathogenic and encompasses more than 2600 …

Salmonella enterica serovar Typhi produces significant morbidity and mortality worldwide
despite the fact that there are licensed Salmonella Typhi vaccines available. This is primarily …

Background. To expedite the evaluation of vaccines against paratyphoid fever, we aimed to
develop the first human challenge model of Salmonella enterica serovar Paratyphi A …

Introduction The public health burden caused by pathogenic Gram-negative bacteria is
increasingly prominent due to antimicrobial resistance. The surface carbohydrates are …

Despite the increasing availability of typhoid vaccine in many regions, global estimates of
mortality attributable to enteric fever appear stable. While both Salmonella enterica serovar …

Polysaccharides are often the most abundant antigens found on the extracellular surfaces of
bacterial cells. These polysaccharides play key roles in interactions with the outside world …