Cellular actin networks exhibit a wide range of sizes, shapes, and architectures tailored to
their biological roles. Once assembled, these filamentous networks are either maintained in …

Epithelial cells from diverse tissues, including the enterocytes that line the intestinal tract,
remodel their apical surface during differentiation to form a brush border: an array of actin …

Actin remodeling is at the heart of the response of cells to external or internal stimuli,
allowing a variety of membrane protrusions to form. Fifteen years ago, tunneling nanotubes …

Summary Myosin XVa (MyoXVa) and its cargo whirlin are implicated in deafness and
vestibular dysfunction and have been shown to localize at stereocilia tips and to be essential …

Abstract Tunneling Nanotubes (TNTs) are actin enriched filopodia-like protrusions that play
a pivotal role in long-range intercellular communication. Different pathogens use TNT-like …

Endothelial cell–cell adherens junctions (AJs) supervise fundamental vascular functions,
such as the control of permeability and transmigration of circulating leukocytes, and the …

Tunnelling nanotubes (TNTs) connect distant cells and mediate cargo transfer for
intercellular communication in physiological and pathological contexts. How cells generate …

Sensory neurons use specialized apical processes to perceive external stimuli and monitor
internal body conditions. The apical apparatus can include cilia, microvilli, or both, and is …

Within the confines of tissues, cancer cells can use blebs to migrate. Eps8 is an actin
bundling and capping protein whose capping activity is inhibited by Erk, a key MAP kinase …

Filopodia are adhesive cellular protrusions specialized in the detection of extracellular
matrix (ECM)-derived cues. Although ECM engagement at focal adhesions is known to …