Nitrones are important compounds and are highly useful in many aspects. The first part
describes the methods for synthesis of nitrones, which are useful and environmentally …

Nucleophilic addition to amides has been recognized as a promising transformation for total
synthesis of complex alkaloids. Amides can accept two different organometallic reagents …

As one of the most powerful trifluoromethylation reagents,(trifluoromethyl) trimethylsilane
(TMSCF3) has been widely used for the synthesis of fluorine-containing molecules …

The tertiary amide is a ubiquitous functional group and plays an irreplaceable role in
medicinal chemistry. Its robust nature has meant—in the past—that selective manipulation of …

A new iridium‐catalyzed reductive Strecker reaction for the direct and efficient formation of α‐
amino nitrile products from a broad range of (hetero) aromatic and aliphatic tertiary amides …

A variety of inert tertiary amides have been successfully transformed into synthetically
important chiral propargylamines in high yields with good to excellent enantioselectivities …

Amides are ubiquitous in the fine chemical, agrochemical and pharmaceutical industries, but
are rarely exploited as substrates for homologous amine synthesis. By virtue of their high …

A unified total synthesis of stemoamide-type alkaloids is reported. Our synthetic approach
features the chemoselective convergent assembly of five-membered building blocks via …

Reactivity umpolung is an important concept in organic chemistry. Established reactivity
umpolung mainly focuses on the aldehyde and umpolung of amide carbonyl group is not …

A new iridium catalyzed reductive coupling reaction of Grignard reagents and tertiary
amides affording functionalised tertiary amine products via an efficient and technically …