Topography-mediated immunomodulation in osseointegration; Ally or Enemy

S Shirazi, S Ravindran, LF Cooper - Biomaterials, 2022 - Elsevier
Osteoimmunology is at full display during endosseous implant osseointegration. Bone
formation, maintenance and resorption at the implant surface is a result of bidirectional and …

Biofunctional elements incorporated nano/microstructured coatings on titanium implants with enhanced osteogenic and antibacterial performance

N Xu, J Fu, L Zhao, PK Chu… - Advanced Healthcare …, 2020 - Wiley Online Library
Bone fracture is prevalent among athletes and senior citizens and may require surgical
insertion of bone implants. Titanium (Ti) and its alloys are widely used in orthopedics due to …

[HTML][HTML] Transition metals in angiogenesis–a narrative review

J Dürig, M Calcagni, J Buschmann - Materials Today Bio, 2023 - Elsevier
The aim of this paper is to offer a narrative review of the literature regarding the influence of
transition metals on angiogenesis, excluding lanthanides and actinides. To our knowledge …

Hierarchical micro-nano topography promotes cell adhesion and osteogenic differentiation via integrin α2-PI3K-AKT signaling axis

H Zheng, Y Tian, Q Gao, Y Yu, X Xia, Z Feng… - … in bioengineering and …, 2020 - frontiersin.org
Surface topography dictates important aspects of cell biological behaviors. In our study,
hierarchical micro-nano topography (SLM-AHT) with micro-scale grooves and nano-scale …

[HTML][HTML] Incorporation of Sr2+ and Ag nanoparticles into TiO2 nanotubes to synergistically enhance osteogenic and antibacterial activities for bone repair

C Pan, T Liu, Y Yang, T Liu, Z Gong, Y Wei, L Quan… - Materials & Design, 2020 - Elsevier
Osteogenic and antibacterial activities are two basic requirements for orthopedic implants.
The present study mainly focused on the investigation of the osteoblast behaviors and …

[HTML][HTML] A microporous surface containing Si3N4/Ta microparticles of PEKK exhibits both antibacterial and osteogenic activity for inducing cellular response and …

X Hu, S Mei, F Wang, S Tang, D Xie, C Ding, W Du… - Bioactive materials, 2021 - Elsevier
As an implantable biomaterial, polyetherketoneketone (PEKK) exhibits good mechanical
strength but it is biologically inert while tantalum (Ta) possesses outstanding osteogenic …

NanoZnO-modified titanium implants for enhanced anti-bacterial activity, osteogenesis and corrosion resistance

Z Wang, X Wang, Y Wang, Y Zhu, X Liu… - Journal of …, 2021 - Springer
Titanium (Ti) implants are widely used in dentistry and orthopedics owing to their excellent
corrosion resistance, biocompatibility, and mechanical properties, which have gained …

Enhanced VEGF/VEGF-R and RUNX2 expression in human periodontal ligament stem cells cultured on sandblasted/etched titanium disk

GD Marconi, F Diomede, J Pizzicannella… - Frontiers in cell and …, 2020 - frontiersin.org
Bone formation, in skeletal development or in osseointegration processes, is the result of
interaction between angiogenesis and osteogenesis. To establish osseointegration, cells …

Engineering biomimetic extracellular matrix with silica nanofibers: from 1D material to 3D network

J Zhou, Y Nie, C Jin, JXJ Zhang - ACS Biomaterials Science & …, 2022 - ACS Publications
Biomaterials at nanoscale is a fast-expanding research field with which extensive studies
have been conducted on understanding the interactions between cells and their …

[HTML][HTML] Beta1-integrin/Hedgehog-Gli1 signaling pathway fuels the diameter-dependent osteoblast differentiation on different TiO2 nanotubes: The optimal-diameter …

Y Xie, X Chen, X Zheng, L Li, J Li, Y Xu, J He… - The international journal …, 2021 - Elsevier
Micro/nanotextured topographies (MNTs) can modulate cell-biomaterial interactions mostly
by their controllable geometrics. Among them, TiO 2 nanotubes, regarded as having a highly …