Ribonucleases (RNases) are mediators in most reactions of RNA metabolism. In recent
years, there has been a surge of new information about RNases and the roles they play in …

The continuous degradation and synthesis of prokaryotic mRNAs not only give rise to the
metabolic changes that are required as cells grow and divide but also rapid adaptation to …

Human immunodeficiency virus type 1 (HIV-1) gene expression is activated by Tat, a virally
encoded protein. Tat trans-activation requires viral (trans-activation—responsive; TAR) RNA …

Conservation of microRNAs (miRNAs) among species suggests that they bear conserved
biological functions. However, sequencing of new miRNAs has not always been …

Abstract Background: Aquifex aeolicus Ribonuclease III (Aa-RNase III) belongs to the family
of Mg 2+-dependent endonucleases that show specificity for double-stranded RNA (dsRNA) …

Members of the large superclass of P-loop GTPases share a core domain with a conserved
three-dimensional structure. In eukaryotes, these proteins are implicated in various crucial …

The maturation and degradation of RNA molecules are essential features of the mechanism
of gene expression, and provide the two main points for post-transcriptional regulation. Cells …

▪ Abstract The stability of mRNA in prokaryotes depends on multiple factors and it has not yet
been possible to describe the process of mRNA degradation in terms of a unique pathway …

Bacteria have a remarkable ability to sense environmental changes, swiftly regulating their
transcriptional and posttranscriptional machinery as a response. Under conditions that …

The instability of messenger RNA is fundamental to the control of gene expression. In
bacteria, mRNA degradation generally follows an “all-or-none” pattern. This implies that if …