[HTML][HTML] Cardiovascular optoacoustics: From mice to men–A review
Imaging has become an indispensable tool in the research and clinical management of
cardiovascular disease (CVD). An array of imaging technologies is considered for CVD …
cardiovascular disease (CVD). An array of imaging technologies is considered for CVD …
Obligatory role for B cells in the development of angiotensin II–dependent hypertension
Clinical hypertension is associated with raised serum IgG antibodies. However, whether
antibodies are causative agents in hypertension remains unknown. We investigated whether …
antibodies are causative agents in hypertension remains unknown. We investigated whether …
Non-invasive imaging of CSF-mediated brain clearance pathways via assessment of perivascular fluid movement with diffusion tensor MRI
The glymphatics system describes a CSF-mediated clearance pathway for the removal of
potentially harmful molecules, such as amyloid beta, from the brain. As such, its components …
potentially harmful molecules, such as amyloid beta, from the brain. As such, its components …
Progressive aortic stiffness in aging C57Bl/6 mice displays altered contractile behaviour and extracellular matrix changes
S De Moudt, JO Hendrickx, C Neutel… - Communications …, 2022 - nature.com
Aortic stiffness is a hallmark of cardiovascular disease, but its pathophysiology remains
incompletely understood. This study presents an in-dept characterization of aortic aging in …
incompletely understood. This study presents an in-dept characterization of aortic aging in …
Imaging techniques for aortic aneurysms and dissections in mice: comparisons of ex vivo, in situ, and ultrasound approaches
Aortic aneurysms and dissections are life-threatening conditions that have a high risk for
lethal bleeding and organ malperfusion. Many studies have investigated the molecular basis …
lethal bleeding and organ malperfusion. Many studies have investigated the molecular basis …
Doxorubicin-induced cardiovascular toxicity: a longitudinal evaluation of functional and molecular markers
M Bosman, D Krüger, C Van Assche… - Cardiovascular …, 2023 - academic.oup.com
Aims Apart from cardiotoxicity, the chemotherapeutic doxorubicin (DOX) induces vascular
toxicity, represented by arterial stiffness and endothelial dysfunction. Both parameters are of …
toxicity, represented by arterial stiffness and endothelial dysfunction. Both parameters are of …
Mitochondrial P2X7 receptor localization modulates energy metabolism enhancing physical performance
AC Sarti, V Vultaggio-Poma, S Falzoni, S Missiroli… - Function, 2021 - academic.oup.com
Basal expression of the P2X7 receptor (P2X7R) improves mitochondrial metabolism,
Adenosine 5′-triphosphate (ATP) synthesis, and overall fitness of immune and non …
Adenosine 5′-triphosphate (ATP) synthesis, and overall fitness of immune and non …
Doxorubicin impairs smooth muscle cell contraction: novel insights in vascular toxicity
M Bosman, DN Krüger, K Favere, CD Wesley… - International journal of …, 2021 - mdpi.com
Clinical and animal studies have demonstrated that chemotherapeutic doxorubicin (DOX)
increases arterial stiffness, a predictor of cardiovascular risk. Despite consensus about DOX …
increases arterial stiffness, a predictor of cardiovascular risk. Despite consensus about DOX …
Doxorubicin induces arterial stiffness: A comprehensive in vivo and ex vivo evaluation of vascular toxicity in mice
M Bosman, K Favere, CHG Neutel, G Jacobs… - Toxicology Letters, 2021 - Elsevier
Arterial stiffness is an important predictor of cardiovascular risk. Clinical studies have
demonstrated that arterial stiffness increases in cancer patients treated with the …
demonstrated that arterial stiffness increases in cancer patients treated with the …
A 6-month systems toxicology inhalation study in ApoE−/− mice demonstrates reduced cardiovascular effects of E-vapor aerosols compared with cigarette smoke
Smoking cigarettes is harmful to the cardiovascular system. Considerable attention has
been paid to the reduced harm potential of alternative nicotine-containing inhalable …
been paid to the reduced harm potential of alternative nicotine-containing inhalable …