[HTML][HTML] Cardiovascular optoacoustics: From mice to men–A review

A Karlas, NA Fasoula, K Paul-Yuan, J Reber… - Photoacoustics, 2019 - Elsevier
Imaging has become an indispensable tool in the research and clinical management of
cardiovascular disease (CVD). An array of imaging technologies is considered for CVD …

Obligatory role for B cells in the development of angiotensin II–dependent hypertension

CT Chan, CG Sobey, M Lieu, D Ferens, MM Kett… - …, 2015 - Am Heart Assoc
Clinical hypertension is associated with raised serum IgG antibodies. However, whether
antibodies are causative agents in hypertension remains unknown. We investigated whether …

Non-invasive imaging of CSF-mediated brain clearance pathways via assessment of perivascular fluid movement with diffusion tensor MRI

IF Harrison, B Siow, AB Akilo, PG Evans, O Ismail… - Elife, 2018 - elifesciences.org
The glymphatics system describes a CSF-mediated clearance pathway for the removal of
potentially harmful molecules, such as amyloid beta, from the brain. As such, its components …

Progressive aortic stiffness in aging C57Bl/6 mice displays altered contractile behaviour and extracellular matrix changes

S De Moudt, JO Hendrickx, C Neutel… - Communications …, 2022 - nature.com
Aortic stiffness is a hallmark of cardiovascular disease, but its pathophysiology remains
incompletely understood. This study presents an in-dept characterization of aortic aging in …

Imaging techniques for aortic aneurysms and dissections in mice: comparisons of ex vivo, in situ, and ultrasound approaches

S Ito, HS Lu, A Daugherty, H Sawada - Biomolecules, 2022 - mdpi.com
Aortic aneurysms and dissections are life-threatening conditions that have a high risk for
lethal bleeding and organ malperfusion. Many studies have investigated the molecular basis …

Doxorubicin-induced cardiovascular toxicity: a longitudinal evaluation of functional and molecular markers

M Bosman, D Krüger, C Van Assche… - Cardiovascular …, 2023 - academic.oup.com
Aims Apart from cardiotoxicity, the chemotherapeutic doxorubicin (DOX) induces vascular
toxicity, represented by arterial stiffness and endothelial dysfunction. Both parameters are of …

Mitochondrial P2X7 receptor localization modulates energy metabolism enhancing physical performance

AC Sarti, V Vultaggio-Poma, S Falzoni, S Missiroli… - Function, 2021 - academic.oup.com
Basal expression of the P2X7 receptor (P2X7R) improves mitochondrial metabolism,
Adenosine 5′-triphosphate (ATP) synthesis, and overall fitness of immune and non …

Doxorubicin impairs smooth muscle cell contraction: novel insights in vascular toxicity

M Bosman, DN Krüger, K Favere, CD Wesley… - International journal of …, 2021 - mdpi.com
Clinical and animal studies have demonstrated that chemotherapeutic doxorubicin (DOX)
increases arterial stiffness, a predictor of cardiovascular risk. Despite consensus about DOX …

Doxorubicin induces arterial stiffness: A comprehensive in vivo and ex vivo evaluation of vascular toxicity in mice

M Bosman, K Favere, CHG Neutel, G Jacobs… - Toxicology Letters, 2021 - Elsevier
Arterial stiffness is an important predictor of cardiovascular risk. Clinical studies have
demonstrated that arterial stiffness increases in cancer patients treated with the …

A 6-month systems toxicology inhalation study in ApoE−/− mice demonstrates reduced cardiovascular effects of E-vapor aerosols compared with cigarette smoke

J Szostak, ET Wong, B Titz, T Lee… - American Journal …, 2020 - journals.physiology.org
Smoking cigarettes is harmful to the cardiovascular system. Considerable attention has
been paid to the reduced harm potential of alternative nicotine-containing inhalable …