Precursor lesions for sporadic pancreatic cancer: PanIN, IPMN, and MCN
M Distler, D Aust, J Weitz, C Pilarsky… - BioMed research …, 2014 - Wiley Online Library
Pancreatic cancer is still a dismal disease. The high mortality rate is mainly caused by the
lack of highly sensitive and specific diagnostic tools, and most of the patients are diagnosed …
lack of highly sensitive and specific diagnostic tools, and most of the patients are diagnosed …
Cystic precursors to invasive pancreatic cancer
H Matthaei, RD Schulick, RH Hruban… - Nature reviews …, 2011 - nature.com
Improvements in the sensitivity and quality of cross-sectional imaging have led to increasing
numbers of patients being diagnosed with cystic lesions of the pancreas. In parallel, clinical …
numbers of patients being diagnosed with cystic lesions of the pancreas. In parallel, clinical …
Recurrent GNAS Mutations Define an Unexpected Pathway for Pancreatic Cyst Development
More than 2% of the adult US population harbors a pancreatic cyst. These often pose a
difficult management problem because conventional criteria cannot always distinguish cysts …
difficult management problem because conventional criteria cannot always distinguish cysts …
Systematic review of challenging issues in pathology of intraductal papillary mucinous neoplasms
Abstract Background/Objectives: Intraductal papillary mucinous neoplasms (IPMNs) are a
cystic precursor to pancreatic cancer. IPMNs deemed clinically to be at high-risk for …
cystic precursor to pancreatic cancer. IPMNs deemed clinically to be at high-risk for …
From somatic mutation to early detection: insights from molecular characterization of pancreatic cancer precursor lesions
CG Fischer, LD Wood - The Journal of pathology, 2018 - Wiley Online Library
Pancreatic cancer arises from noninvasive precursor lesions, including pancreatic
intraepithelial neoplasia (PanIN), intraductal papillary mucinous neoplasm (IPMN), and …
intraepithelial neoplasia (PanIN), intraductal papillary mucinous neoplasm (IPMN), and …
[HTML][HTML] Integration of KRAS testing in the diagnosis of pancreatic cystic lesions: a clinical experience of 618 pancreatic cysts
MN Nikiforova, A Khalid, KE Fasanella, KM McGrath… - Modern …, 2013 - nature.com
With improvements in abdominal imaging, detection of incidental pancreatic cysts are
becoming increasingly common. Analysis of pancreatic cyst fluid from fine-needle aspiration …
becoming increasingly common. Analysis of pancreatic cyst fluid from fine-needle aspiration …
Intraductal papillary mucinous tumors of the pancreas: biology, diagnosis, and treatment
R Grützmann, M Niedergethmann, C Pilarsky… - The …, 2010 - academic.oup.com
Pancreatic intraductal papillary mucinous neoplasms (IPMNs) rank among the most
common cystic tumors of the pancreas. For a long time they were misdiagnosed as …
common cystic tumors of the pancreas. For a long time they were misdiagnosed as …
[HTML][HTML] Genetic and epigenetic alterations in pancreatic carcinogenesis
Y Delpu, N Hanoun, H Lulka, F Sicard, J Selves… - Current …, 2011 - ncbi.nlm.nih.gov
Pancreatic ductal adenocarcinoma (PDAC) is one of the most lethal cancers worldwide.
Despite significant progresses in the last decades, the origin of this cancer remains unclear …
Despite significant progresses in the last decades, the origin of this cancer remains unclear …
Clinicopathological characteristics and molecular analyses of multifocal intraductal papillary mucinous neoplasms of the pancreas
H Matthaei, AL Norris, AC Tsiatis, K Olino… - Annals of …, 2012 - journals.lww.com
Objective: To examine the clinicopathologic features and clonal relationship of multifocal
intraductal papillary mucinous neoplasms (IPMNs) of the pancreas. Background: Intraductal …
intraductal papillary mucinous neoplasms (IPMNs) of the pancreas. Background: Intraductal …