Abnormal aggregation of tau in the brain is a major contributing factor in various
neurodegenerative diseases. The role of tau phosphorylation in the pathophysiology of …

Overview of tau PET molecular imaging : Current Opinion in Neurology Overview of tau PET
molecular imaging : Current Opinion in Neurology Log in or Register Subscribe to journalSubscribe …

The pathological potential of human astroglia in Alzheimer's disease (AD) was analysed in
vitro using induced pluripotent stem cell (iPSC) technology. Here, we report development of …

Alzheimer's disease (AD) is characterized by the brain accumulation of amyloid-β and tau
proteins. A growing body of literature suggests that epigenetic dysregulations play a role in …

Measuring synaptic density in vivo using positron emission tomography (PET) imaging-
based biomarkers targeting the synaptic vesicle protein 2A (SV2A) has received much …

Pathological accumulated misfolded tau underlies various neurodegenerative diseases and
associated clinical syndromes. To diagnose those diseases reliable before death or even at …

Purpose Second-generation tau radiotracers for use with positron emission tomography
(PET) have been developed for visualization of tau deposits in vivo. For several β-amyloid …

There is growing evidence that chronic brain hypoperfusion plays a central role in the
development of Alzheimer's disease (AD) long before dyscognitive symptoms or amyloid-β …

Sporadic cerebral amyloid angiopathy (CAA) is a very common small vessel disease of the
brain, showing preferential and progressive amyloid-βdeposition in the wall of small …

Purpose We aimed to investigate associations between tau pathology and relative cerebral
blood flow (rCBF), and their relationship with cognition in Alzheimer's disease (AD), by using …