Various environmental stressors, such as extreme temperatures (hot and cold), pathogens,
predators and insufficient food, can threaten life. Remarkable progress has recently been …

This brief review, which is based on a lecture presented at the American Physiological
Society Teaching Refresher Course on the Brain and Systems Control as part of the …

Single-cell RNA-sequencing (scRNA-seq) is an indispensable tool for characterizing cellular
diversity and generating hypotheses throughout biology. Droplet-based scRNA-seq datasets …

The advent of endothermy, which is achieved through the continuous homeostatic regulation
of body temperature and metabolism,, is a defining feature of mammalian and avian …

Water deprivation produces a drive to seek and consume water. How neural activity creates
this motivation remains poorly understood. We used activity-dependent genetic labeling to …

Thirst motivates animals to find and consume water. More than 40 years ago, a set of
interconnected brain structures known as the lamina terminalis was shown to govern thirst …

Thermoregulation is one of the most vital functions of the brain, but how temperature
information is converted into homeostatic responses remains unknown. Here, we use an …

Abstract The “dorsal pons”, or “dorsal pontine tegmentum”(dPnTg), is part of the brainstem. It
is a complex, densely packed region whose nuclei are involved in regulating many vital …

Central neural circuits orchestrate the behavioral and autonomic repertoire that maintains
body temperature during environmental temperature challenges and alters body …

Central neural circuits orchestrate the homeostatic repertoire that maintains body
temperature during environmental temperature challenges and alters body temperature …