Dissecting the causal mechanism of X-linked dystonia-parkinsonism by integrating genome and transcriptome assembly
Summary X-linked Dystonia-Parkinsonism (XDP) is a Mendelian neurodegenerative
disease that is endemic to the Philippines and is associated with a founder haplotype. We …
disease that is endemic to the Philippines and is associated with a founder haplotype. We …
Inhibiting epileptiform activity in cognitive disorders: possibilities for a novel therapeutic approach
AA Horvath, EA Csernus, S Lality… - Frontiers in …, 2020 - frontiersin.org
Cognitive impairment is a common and seriously debilitating symptom of various mental and
neurological disorders including autism, attention deficit hyperactivity disorder, multiple …
neurological disorders including autism, attention deficit hyperactivity disorder, multiple …
Emerging insights into the structure and function of ionotropic glutamate delta receptors
AP Burada, R Vinnakota, P Bharti… - British Journal of …, 2022 - Wiley Online Library
Glutamate delta‐1 (GluD1) and delta‐2 (GluD2) receptors belong to the orphan GluD
subfamily of ionotropic glutamate receptors (iGluRs). GluDs were classified as ionotropic …
subfamily of ionotropic glutamate receptors (iGluRs). GluDs were classified as ionotropic …
Functional analysis of gut microbiota and immunoinflammation in children with autism spectrum disorders
C Carissimi, I Laudadio, F Palone, V Fulci… - Digestive and Liver …, 2019 - Elsevier
Abstract Background and Aims Recent evidence implicates gut microbiota (GM) and
immune alterations in autism spectrum disorders (ASD). We assess GM profile and …
immune alterations in autism spectrum disorders (ASD). We assess GM profile and …
The first sheep graph-based pan-genome reveals the spectrum of structural variations and their effects on tail phenotypes
R Li, M Gong, X Zhang, F Wang, Z Liu, L Zhang, M Xu… - BioRxiv, 2021 - biorxiv.org
Structural variations (SVs) are a major contributor of genetic diversity and phenotypic
variations, however their prevalence and functions in domestic animals are largely …
variations, however their prevalence and functions in domestic animals are largely …
Genome-wide selection signatures analysis of litter size in Dazu black goats using single-nucleotide polymorphism
XH Duan, JH Zhang, YF Huang, YJ Zhao, RS Na… - 3 Biotech, 2019 - Springer
Litter size is considered to be the most important index for estimating domestic animal
productivity. The number of indigenous goats in China with higher litter sizes than those of …
productivity. The number of indigenous goats in China with higher litter sizes than those of …
EpiMOGA: an epistasis detection method based on a multi-objective genetic algorithm
Y Chen, F Xu, C Pian, M Xu, L Kong, J Fang, Z Li… - Genes, 2021 - mdpi.com
In genome-wide association studies, detecting high-order epistasis is important for
analyzing the occurrence of complex human diseases and explaining missing heritability …
analyzing the occurrence of complex human diseases and explaining missing heritability …
DNA methylation as a potential mediator of the association between indoor air pollution and neurodevelopmental delay in a South African birth cohort
D Feil, S Abrishamcar, GM Christensen, A Vanker… - Clinical …, 2023 - Springer
Background Exposure to indoor air pollution during pregnancy has been linked to
neurodevelopmental delay in toddlers. Epigenetic modification, particularly DNA methylation …
neurodevelopmental delay in toddlers. Epigenetic modification, particularly DNA methylation …
Abnormalities in interactions of Rho GTPases with scaffolding proteins contribute to neurodevelopmental disorders
A Reichova, M Zatkova, Z Bacova… - Journal of neuroscience …, 2018 - Wiley Online Library
Accumulating evidence suggests that Rho GTPases, together with scaffolding SHANK
proteins, and associated signaling pathways play a role in the development of autism …
proteins, and associated signaling pathways play a role in the development of autism …
Proteome profiling of different rat brain regions reveals the modulatory effect of prolonged maternal separation on proteins involved in cell death-related processes
Z Drastichova, V Rudajev, G Pallag, J Novotny - Biological research, 2021 - SciELO Chile
Resumen DRASTICHOVA, Zdenka; RUDAJEV, Vladimir; PALLAG, Gergely y NOVOTNY,
Jiri. Proteome profiling of different rat brain regions reveals the modulatory effect of …
Jiri. Proteome profiling of different rat brain regions reveals the modulatory effect of …