Alzheimer's disease (AD) is one of the most prevalent neurodegenerative disorder. It is
characterized by the formation of amyloid plaques and neurofibrillary tangles in the brain …

Alzheimer's disease (AD) is the most common type of neurodegenerative amyloid disorder
causing progressive cognitive decline and memory loss. A considerable number of …

Insulin degrading enzyme (IDE) is believed to act as a junction point of Type 2 diabetes
(T2D) and Alzheimer's disease (AD); however, the underlying mechanism was not …

Considering the high rate of epilepsy today, with respect to the insufficiency of the available
therapies, new strategies and methods are recommended for medical treatment of epileptic …

Abstract Type 2 diabetes (T2D) may play a relevant role in the development of Alzheimer's
disease (AD), however, the underlying mechanism was not clear yet. We developed an …

With respect to the main role of amyloid-β (Aβ) plaques as one of the pathological hallmarks
in the brain of Alzheimer's patients, the development of new imaging probes for targeted …

Methods In this study, training trials of all groups of animals were conducted in the MWM
task. Rats received one training session consisting of four trials per day which continued for …

The hippocampus has an essential role in learning and memory and is a target for androgen
actions. Thus, the effect of testosterone and its metabolites on learning and memory has …

Several lines of evidence show that cAMP-PKA signaling pathway plays critical role in
memory functions and suggest nitric oxide as an important modulator in learning and …

Alzheimer's disease (AD) is the most prevalent neurodegenerative disorder. It is
characterized by formation of amyloid plaques and neurofibrillary tangles in the brain …