The obesity pandemic increasingly causes morbidity and mortality from type 2 diabetes,
cardiovascular diseases and many other chronic diseases. Fat cell size (FCS) predicts …

Obesity is strongly associated with metabolic syndrome. Recent research suggests that
excess adipose tissue plays an important role in development of the syndrome. On the other …

Alterations in the inflammatory state, metabolic function, and structure of subcutaneous
adipose tissue (SAT) can impact the development of insulin resistance in obesity. Exercise …

Insulin inhibits systemic nonesterified fatty acid (NEFA) flux to a greater degree than glucose
or any other metabolite. This remarkable effect is mainly due to insulin-mediated inhibition of …

Fatty acid sources and their fluxes as they contribute to pl... : Current Opinion in Lipidology Fatty
acid sources and their fluxes as they contribute to plasma triglyceride concentrations and fatty …

Background and Aims It is proposed that impaired expansion of subcutaneous adipose
tissue (SAT) and an increase in adipose tissue (AT) fibrosis causes ectopic lipid …

Obesity is associated with body fat gain and impaired glucose metabolism. Here, we
identified both body fat gain in obesity and impaired glucose metabolism as two …

Background and Aims Intrahepatic cholangiocarcinoma (ICC) is the second most common
primary liver cancer and a highly lethal malignancy. Chemotherapeutic options are limited …

Indirect evidence suggests that impaired triglyceride storage in the subcutaneous fat depot
contributes to the development of insulin resistance via lipotoxicity. We directly tested this …

Patterns of abdominal fat distribution (for example, a high vs. low visceral adipose tissue
[VAT]/[VAT+ subcutaneous adipose tissue (SAT)] ratio), independent of obesity, during …