Sensory photoreceptors underpin light-dependent adaptations of organismal physiology,
development, and behavior in nature. Adapted for optogenetics, sensory photoreceptors …

Phototropins are blue-light receptors controlling a range of responses that serve to optimize
the photosynthetic efficiency of plants. These include phototropism, light-induced stomatal …

LOVTRAP is an optogenetic approach for reversible light-induced protein dissociation using
protein A fragments that bind to the LOV domain only in the dark, with tunable kinetics and …

The precise spatio-temporal dynamics of protein activity are often critical in determining cell
behaviour, yet for most proteins they remain poorly understood; it remains difficult to …

Naturally photoswitchable proteins offer a means of directly manipulating the formation of
protein complexes that drive a diversity of cellular processes. We developed tunable light …

Formins are potent activators of actin filament assembly in the cytoplasm. In turn,
cytoplasmic actin polymerization can promote release of actin from megakaryocytic acute …

Plants depend on the surrounding light environment to direct their growth. Blue light (300–
500 nm) in particular acts to promote a wide variety of photomorphogenic responses …

Signaling photoreceptors use the information contained in the absorption of a photon to
modulate biological activity in plants and a wide range of organisms. The fundamental—and …

A growing number of optogenetic tools have been developed to reversibly control binding
between two engineered protein domains. In contrast, relatively few tools confer light …

Plant-based photosensors, such as the light-oxygen-voltage sensing domain 2 (LOV2) from
oat phototropin 1, can be modularly wired into cell signaling networks to remotely control …