Defining roles of specific reactive oxygen species (ROS) in cell biology and physiology

H Sies, VV Belousov, NS Chandel, MJ Davies… - … reviews Molecular cell …, 2022 - nature.com
Abstract 'Reactive oxygen species'(ROS) is a generic term that defines a wide variety of
oxidant molecules with vastly different properties and biological functions that range from …

Mitochondrial fission protein 1: emerging roles in organellar form and function in health and disease

UK Ihenacho, KA Meacham, MC Harwig… - Frontiers in …, 2021 - frontiersin.org
Mitochondrial fission protein 1 (Fis1) was identified in yeast as being essential for
mitochondrial division or fission and subsequently determined to mediate human …

[HTML][HTML] Maintaining social contacts: The physiological relevance of organelle interactions

BSC Silva, L DiGiovanni, R Kumar… - … et Biophysica Acta (BBA …, 2020 - Elsevier
Membrane-bound organelles in eukaryotic cells form an interactive network to coordinate
and facilitate cellular functions. The formation of close contacts, termed “membrane contact …

Molecular insights into peroxisome homeostasis and peroxisome biogenesis disorders

Y Fujiki, K Okumoto, M Honsho, Y Abe - Biochimica et Biophysica Acta …, 2022 - Elsevier
Peroxisomes are single-membrane organelles essential for cell metabolism including the β-
oxidation of fatty acids, synthesis of etherlipid plasmalogens, and redox homeostasis …

Genetic disorders of cellular trafficking

A García-Cazorla, A Oyarzábal, JM Saudubray… - Trends in Genetics, 2022 - cell.com
Cellular trafficking is essential to maintain critical biological functions. Mutations in 346
genes, most of them described in the last 5 years, are associated with disorders of cellular …

[HTML][HTML] The interplay between mitochondrial dynamics and autophagy: From a key homeostatic mechanism to a driver of pathology

A Lacombe, L Scorrano - Seminars in Cell & Developmental Biology, 2024 - Elsevier
The complex relationship between mitochondrial dynamics and autophagy illustrates how
two cellular housekeeping processes are intimately linked, illuminating fundamental …

Determinants of peroxisome membrane dynamics

RE Carmichael, M Schrader - Frontiers in Physiology, 2022 - frontiersin.org
Organelles within the cell are highly dynamic entities, requiring dramatic morphological
changes to support their function and maintenance. As a result, organelle membranes are …

Peroxisomal homeostasis in metabolic diseases and its implication in ferroptosis

J Han, D Zheng, PS Liu, S Wang, X Xie - Cell Communication and …, 2024 - Springer
Peroxisomes are dynamic organelles involved in various cellular processes, including lipid
metabolism, redox homeostasis, and intracellular metabolite transfer. Accumulating …

PEX11β and FIS1 cooperate in peroxisome division independently of mitochondrial fission factor

TA Schrader, RE Carmichael, M Islinger… - Journal of Cell …, 2022 - journals.biologists.com
Peroxisome membrane dynamics and division are essential to adapt the peroxisomal
compartment to cellular needs. The peroxisomal membrane protein PEX11β (also known as …

Mff oligomerization is required for Drp1 activation and synergy with actin filaments during mitochondrial division

A Liu, F Kage, HN Higgs - Molecular Biology of the Cell, 2021 - Am Soc Cell Biol
Mitochondrial division is an important cellular process in both normal and pathological
conditions. The dynamin GTPase Drp1 is a central mitochondrial division protein, driving …