Defining roles of specific reactive oxygen species (ROS) in cell biology and physiology
Abstract 'Reactive oxygen species'(ROS) is a generic term that defines a wide variety of
oxidant molecules with vastly different properties and biological functions that range from …
oxidant molecules with vastly different properties and biological functions that range from …
Mitochondrial fission protein 1: emerging roles in organellar form and function in health and disease
UK Ihenacho, KA Meacham, MC Harwig… - Frontiers in …, 2021 - frontiersin.org
Mitochondrial fission protein 1 (Fis1) was identified in yeast as being essential for
mitochondrial division or fission and subsequently determined to mediate human …
mitochondrial division or fission and subsequently determined to mediate human …
[HTML][HTML] Maintaining social contacts: The physiological relevance of organelle interactions
BSC Silva, L DiGiovanni, R Kumar… - … et Biophysica Acta (BBA …, 2020 - Elsevier
Membrane-bound organelles in eukaryotic cells form an interactive network to coordinate
and facilitate cellular functions. The formation of close contacts, termed “membrane contact …
and facilitate cellular functions. The formation of close contacts, termed “membrane contact …
Molecular insights into peroxisome homeostasis and peroxisome biogenesis disorders
Y Fujiki, K Okumoto, M Honsho, Y Abe - Biochimica et Biophysica Acta …, 2022 - Elsevier
Peroxisomes are single-membrane organelles essential for cell metabolism including the β-
oxidation of fatty acids, synthesis of etherlipid plasmalogens, and redox homeostasis …
oxidation of fatty acids, synthesis of etherlipid plasmalogens, and redox homeostasis …
Genetic disorders of cellular trafficking
A García-Cazorla, A Oyarzábal, JM Saudubray… - Trends in Genetics, 2022 - cell.com
Cellular trafficking is essential to maintain critical biological functions. Mutations in 346
genes, most of them described in the last 5 years, are associated with disorders of cellular …
genes, most of them described in the last 5 years, are associated with disorders of cellular …
[HTML][HTML] The interplay between mitochondrial dynamics and autophagy: From a key homeostatic mechanism to a driver of pathology
A Lacombe, L Scorrano - Seminars in Cell & Developmental Biology, 2024 - Elsevier
The complex relationship between mitochondrial dynamics and autophagy illustrates how
two cellular housekeeping processes are intimately linked, illuminating fundamental …
two cellular housekeeping processes are intimately linked, illuminating fundamental …
Determinants of peroxisome membrane dynamics
RE Carmichael, M Schrader - Frontiers in Physiology, 2022 - frontiersin.org
Organelles within the cell are highly dynamic entities, requiring dramatic morphological
changes to support their function and maintenance. As a result, organelle membranes are …
changes to support their function and maintenance. As a result, organelle membranes are …
Peroxisomal homeostasis in metabolic diseases and its implication in ferroptosis
J Han, D Zheng, PS Liu, S Wang, X Xie - Cell Communication and …, 2024 - Springer
Peroxisomes are dynamic organelles involved in various cellular processes, including lipid
metabolism, redox homeostasis, and intracellular metabolite transfer. Accumulating …
metabolism, redox homeostasis, and intracellular metabolite transfer. Accumulating …
PEX11β and FIS1 cooperate in peroxisome division independently of mitochondrial fission factor
TA Schrader, RE Carmichael, M Islinger… - Journal of Cell …, 2022 - journals.biologists.com
Peroxisome membrane dynamics and division are essential to adapt the peroxisomal
compartment to cellular needs. The peroxisomal membrane protein PEX11β (also known as …
compartment to cellular needs. The peroxisomal membrane protein PEX11β (also known as …
Mff oligomerization is required for Drp1 activation and synergy with actin filaments during mitochondrial division
Mitochondrial division is an important cellular process in both normal and pathological
conditions. The dynamin GTPase Drp1 is a central mitochondrial division protein, driving …
conditions. The dynamin GTPase Drp1 is a central mitochondrial division protein, driving …