Limiting viral replication in hepatocytes alters Rift Valley fever virus disease manifestations

L Xu, AC Paine, DJ Barbeau, F Alencastro… - Journal of …, 2023 - Am Soc Microbiol
Rift Valley fever virus (RVFV) causes mild to severe disease in humans and livestock.
Outbreaks of RVFV have been reported throughout Africa and have spread outside Africa …

[HTML][HTML] The deubiquitinase USP40 preserves endothelial integrity by targeting the heat shock protein HSP90β

J Miao, L Li, N Shaheen, J Wei, AM Jacko… - … & Molecular Medicine, 2024 - nature.com
Endothelial cell (EC) barrier disruption and inflammation are the pathological hallmarks of
vascular disorders and acute infectious diseases and related conditions, including the …

[HTML][HTML] Construction of an IFNAR1 knockout MDBK cell line using CRISPR/Cas9 and its effect on bovine virus replication

Y Geng, C Jiang, H Yang, Q Xia, X Xu, K Yang… - Frontiers in …, 2024 - frontiersin.org
The type I interferon (IFN) pathway is important for eukaryotic cells to resist viral infection, as
well as an impediment to efficient virus replication. Therefore, this study aims to create an …